components: schemas: ACBodyRequest: additionalProperties: false properties: hdl_cholesterol: description: HDL cholesterol value example: 50 exclusiveMinimum: true format: double minimum: 0 type: number hdl_cholesterol_unit: description: Unit of HDL cholesterol measurement enum: - mg/dL - mmol/L example: mg/dL type: string total_cholesterol: description: Total cholesterol value example: 200 exclusiveMinimum: true format: double minimum: 0 type: number total_cholesterol_unit: description: Unit of total cholesterol measurement enum: - mg/dL - mmol/L example: mg/dL type: string required: - total_cholesterol - total_cholesterol_unit - hdl_cholesterol - hdl_cholesterol_unit type: object ACBodyResponse: additionalProperties: false properties: ac: description: Calculated Atherogenic Coefficient example: 3 format: double type: number metadata: $ref: "#/components/schemas/ACMetadata" description: Metadata about the calculation required: - ac - metadata type: object ACMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/ACBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object AGRBodyRequest: additionalProperties: false properties: albumin: description: Albumin value example: 4 exclusiveMinimum: true format: double minimum: 0 type: number albumin_unit: description: Unit of albumin measurement enum: - g/L - g/dL example: g/dL type: string total_protein: description: Total protein value example: 7 exclusiveMinimum: true format: double minimum: 0 type: number total_protein_unit: description: Unit of total protein measurement enum: - g/L - g/dL example: g/dL type: string required: - albumin - albumin_unit - total_protein - total_protein_unit type: object AGRBodyResponse: additionalProperties: false properties: agr: description: Albumin-Globulin Ratio example: 1.33 format: double type: number metadata: $ref: "#/components/schemas/AGRMetadata" description: Metadata about the calculation required: - agr - metadata type: object AGRMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/AGRBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object AIPBodyRequest: additionalProperties: false properties: hdl_cholesterol: description: HDL cholesterol value example: 40 exclusiveMinimum: true format: double minimum: 0 type: number hdl_cholesterol_unit: description: Unit of HDL cholesterol measurement enum: - mmol/L - mg/dL example: mg/dL type: string triglycerides: description: Triglycerides value example: 150 exclusiveMinimum: true format: double minimum: 0 type: number triglycerides_unit: description: Unit of triglycerides measurement enum: - mmol/L - mg/dL example: mg/dL type: string required: - triglycerides - triglycerides_unit - hdl_cholesterol - hdl_cholesterol_unit type: object AIPBodyResponse: additionalProperties: false properties: aip: description: Atherogenic Index of Plasma example: 0.38 format: double type: number metadata: $ref: "#/components/schemas/AIPMetadata" description: Metadata about the calculation risk: description: Cardiovascular risk category example: High type: string required: - aip - risk - metadata type: object AIPMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/AIPBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object ANCBodyRequest: additionalProperties: false properties: band_neutrophils_percent: description: Percentage of band neutrophils example: 5 format: double maximum: 100 minimum: 0 type: number segmented_neutrophils_percent: description: Percentage of segmented neutrophils example: 60 format: double maximum: 100 minimum: 0 type: number wbc_count: description: White blood cell count example: 10000 exclusiveMinimum: true format: double minimum: 0 type: number wbc_count_unit: description: Unit of white blood cell count measurement enum: - cells/µL - 10^9/L example: cells/µL type: string required: - wbc_count - wbc_count_unit - segmented_neutrophils_percent - band_neutrophils_percent type: object ANCBodyResponse: additionalProperties: false properties: anc: $ref: "#/components/schemas/ANCValue" description: Calculated Absolute Neutrophil Count metadata: $ref: "#/components/schemas/ANCMetadata" description: Metadata about the calculation required: - anc - metadata type: object ANCMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/ANCBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object ANCValue: additionalProperties: false properties: cells_per_l: description: ANC in 10^9/L example: 6.5 format: double type: number cells_per_µl: description: ANC in cells/µL example: 6500 format: double type: number required: - cells_per_µl - cells_per_l type: object APRIBodyRequest: additionalProperties: false properties: ast: description: AST (Aspartate Aminotransferase) value example: 50 exclusiveMinimum: true format: double minimum: 0 type: number ast_unit: description: Unit of AST measurement enum: - U/L - µkat/L example: U/L type: string ast_upper_limit: description: Laboratory upper limit of normal for AST example: 40 exclusiveMinimum: true format: double minimum: 0 type: number ast_upper_limit_unit: description: Unit of AST upper limit measurement enum: - U/L - µkat/L example: U/L type: string platelet_count: description: Platelet count value example: 150 exclusiveMinimum: true format: double minimum: 0 type: number platelet_count_unit: description: Unit of platelet count measurement enum: - 10^9/L - 10^3/µL example: 10^9/L type: string required: - ast - ast_unit - platelet_count - platelet_count_unit - ast_upper_limit - ast_upper_limit_unit type: object APRIBodyResponse: additionalProperties: false properties: apri: description: Calculated AST to Platelet Ratio Index example: 0.83 format: double type: number metadata: $ref: "#/components/schemas/APRIMetadata" description: Metadata about the calculation required: - apri - metadata type: object APRIMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/APRIBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object AnionGapBodyRequest: additionalProperties: false properties: bicarbonate: description: Bicarbonate level example: 24 exclusiveMinimum: true format: double minimum: 0 type: number bicarbonate_unit: description: Unit of bicarbonate measurement enum: - mmol/L - mEq/L example: mmol/L type: string chloride: description: Chloride level example: 102 exclusiveMinimum: true format: double minimum: 0 type: number chloride_unit: description: Unit of chloride measurement enum: - mmol/L - mEq/L example: mmol/L type: string potassium: description: Potassium level (optional) example: 4.5 exclusiveMinimum: true format: double minimum: 0 type: number potassium_unit: description: Unit of potassium measurement (required if potassium is provided) enum: - mmol/L - mEq/L example: mmol/L type: string sodium: description: Sodium level example: 140 exclusiveMinimum: true format: double minimum: 0 type: number sodium_unit: description: Unit of sodium measurement enum: - mmol/L - mEq/L example: mmol/L type: string required: - sodium - sodium_unit - chloride - chloride_unit - bicarbonate - bicarbonate_unit type: object AnionGapBodyResponse: additionalProperties: false properties: anion_gap: description: Calculated Anion Gap example: 18.5 format: double type: number metadata: $ref: "#/components/schemas/AnionGapMetadata" description: Metadata about the calculation required: - anion_gap - metadata type: object AnionGapMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/AnionGapBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object ApoRatioBodyRequest: additionalProperties: false properties: apo_a1: description: Apolipoprotein A1 (Apo A1) value example: 1.5 exclusiveMinimum: true format: double minimum: 0 type: number apo_a1_unit: description: Unit of Apo A1 measurement enum: - g/L - mg/dL example: g/L type: string apo_b: description: Apolipoprotein B (Apo B) value example: 1 exclusiveMinimum: true format: double minimum: 0 type: number apo_b_unit: description: Unit of Apo B measurement enum: - g/L - mg/dL example: g/L type: string required: - apo_b - apo_b_unit - apo_a1 - apo_a1_unit type: object ApoRatioBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/ApoRatioMetadata" description: Metadata about the calculation ratio: description: Calculated Apo B/Apo A1 ratio example: 0.67 format: double type: number required: - ratio - metadata type: object ApoRatioMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/ApoRatioBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object BCSTIPSBodyRequest: additionalProperties: false properties: age: description: Age in years example: 50 exclusiveMinimum: true format: int64 minimum: 0 type: integer bilirubin: description: Bilirubin value example: 1.5 exclusiveMinimum: true format: double minimum: 0 type: number bilirubin_unit: description: Unit of bilirubin measurement enum: - mg/dL - µmol/L example: mg/dL type: string inr: description: International Normalized Ratio (INR) for prothrombin time example: 1.2 exclusiveMinimum: true format: double minimum: 0 type: number required: - age - bilirubin - bilirubin_unit - inr type: object BCSTIPSBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/BCSTIPSMetadata" description: Metadata about the calculation prognostic_index: description: Calculated BCS-TIPS Prognostic Index example: 6.5 format: double type: number required: - prognostic_index - metadata type: object BCSTIPSMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/BCSTIPSBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object CRPAlbuminRatioBodyRequest: additionalProperties: false properties: albumin: description: Albumin value example: 35 exclusiveMinimum: true format: double minimum: 0 type: number albumin_unit: description: Unit of albumin measurement enum: - g/L - g/dL example: g/L type: string crp: description: C-reactive protein value example: 5 exclusiveMinimum: true format: double minimum: 0 type: number crp_unit: description: Unit of C-reactive protein measurement enum: - mg/L - mg/dL - nmol/L example: mg/L type: string required: - crp - crp_unit - albumin - albumin_unit type: object CRPAlbuminRatioBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/CRPAlbuminRatioMetadata" description: Metadata about the calculation ratio: description: C-reactive protein to albumin ratio example: 0.1429 format: double type: number required: - ratio - metadata type: object CRPAlbuminRatioMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/CRPAlbuminRatioBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object CaO2BodyRequest: additionalProperties: false properties: hemoglobin: description: Hemoglobin concentration example: 15 exclusiveMinimum: true format: double minimum: 0 type: number hemoglobin_unit: description: Unit of hemoglobin measurement enum: - g/dL - g/L example: g/dL type: string oxygen_saturation: description: Oxygen saturation (SaO2) in % example: 97 format: double maximum: 100 minimum: 0 type: number partial_pressure_oxygen: description: Partial pressure of oxygen (PaO2) example: 95 exclusiveMinimum: true format: double minimum: 0 type: number partial_pressure_oxygen_unit: description: Unit of PaO2 measurement enum: - mmHg - kPa example: mmHg type: string required: - hemoglobin - hemoglobin_unit - oxygen_saturation - partial_pressure_oxygen - partial_pressure_oxygen_unit type: object CaO2BodyResponse: additionalProperties: false properties: cao2: description: Calculated Oxygen Content (mL O2/dL blood) example: 20.1 format: double type: number metadata: $ref: "#/components/schemas/CaO2Metadata" description: Metadata about the calculation required: - cao2 - metadata type: object CaO2Metadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/CaO2BodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object CastelliRiskBodyRequest: additionalProperties: false properties: hdl_cholesterol: description: HDL Cholesterol value example: 50 exclusiveMinimum: true format: double minimum: 0 type: number hdl_cholesterol_unit: description: Unit of HDL Cholesterol measurement enum: - mg/dL - mmol/L example: mg/dL type: string ldl_cholesterol: description: LDL Cholesterol value example: 130 exclusiveMinimum: true format: double minimum: 0 type: number ldl_cholesterol_unit: description: Unit of LDL Cholesterol measurement enum: - mg/dL - mmol/L example: mg/dL type: string total_cholesterol: description: Total Cholesterol value example: 200 exclusiveMinimum: true format: double minimum: 0 type: number total_cholesterol_unit: description: Unit of Total Cholesterol measurement enum: - mg/dL - mmol/L example: mg/dL type: string required: - total_cholesterol - total_cholesterol_unit - ldl_cholesterol - ldl_cholesterol_unit - hdl_cholesterol - hdl_cholesterol_unit type: object CastelliRiskBodyResponse: additionalProperties: false properties: castelli_risk_index_i: description: Castelli Risk Index I (Total Cholesterol / HDL Cholesterol) example: 4 format: double type: number castelli_risk_index_ii: description: Castelli Risk Index II (LDL Cholesterol / HDL Cholesterol) example: 2.6 format: double type: number metadata: $ref: "#/components/schemas/CastelliRiskMetadata" description: Metadata about the calculation required: - castelli_risk_index_i - castelli_risk_index_ii - metadata type: object CastelliRiskMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/CastelliRiskBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object CorrectedCalciumBodyRequest: additionalProperties: false properties: albumin: description: Albumin value example: 4 exclusiveMinimum: true format: double minimum: 0 type: number albumin_unit: description: Unit of albumin measurement enum: - g/L - g/dL example: g/dL type: string total_calcium: description: Total calcium value example: 9.5 exclusiveMinimum: true format: double minimum: 0 type: number total_calcium_unit: description: Unit of total calcium measurement enum: - mmol/L - mg/dL example: mg/dL type: string required: - total_calcium - total_calcium_unit - albumin - albumin_unit type: object CorrectedCalciumBodyResponse: additionalProperties: false properties: corrected_calcium: $ref: "#/components/schemas/CorrectedCalciumValue" description: Calculated corrected calcium values metadata: $ref: "#/components/schemas/CorrectedCalciumMetadata" description: Metadata about the calculation required: - corrected_calcium - metadata type: object CorrectedCalciumMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/CorrectedCalciumBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object CorrectedCalciumValue: additionalProperties: false properties: mg_dl: description: Corrected calcium in mg/dL example: 9.6 format: double type: number mmol_l: description: Corrected calcium in mmol/L example: 2.4 format: double type: number required: - mmol_l - mg_dl type: object CrClBodyRequest: additionalProperties: false properties: age: description: Age in years example: 50 format: int64 maximum: 120 minimum: 18 type: integer gender: description: Gender enum: - male - female example: female type: string height: description: Height of the person example: 170 exclusiveMinimum: true format: double minimum: 0 type: number height_unit: description: Unit of height measurement enum: - cm - in example: cm type: string serum_creatinine: description: Serum creatinine value example: 0.9 exclusiveMinimum: true format: double minimum: 0 type: number serum_creatinine_unit: description: Unit of serum creatinine measurement enum: - mg/dL - µmol/L example: mg/dL type: string weight: description: Weight of the person example: 70 exclusiveMinimum: true format: double minimum: 0 type: number weight_unit: description: Unit of weight measurement enum: - kg - lb example: kg type: string required: - age - gender - weight - weight_unit - height - height_unit - serum_creatinine - serum_creatinine_unit type: object CrClBodyResponse: additionalProperties: false properties: crcl_actual_body_weight: description: Creatinine Clearance using actual body weight (mL/min) example: 92.5 format: double type: number crcl_ideal_body_weight: description: Creatinine Clearance using ideal body weight (mL/min) example: 85 format: double type: number metadata: $ref: "#/components/schemas/CrClMetadata" description: Metadata about the calculation required: - crcl_actual_body_weight - crcl_ideal_body_weight - metadata type: object CrClMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/CrClBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object DFBodyRequest: additionalProperties: false properties: control_time: description: Laboratory control time for prothrombin time in seconds example: 12 exclusiveMinimum: true format: double minimum: 0 type: number prothrombin_time: description: Prothrombin time value in seconds example: 18 exclusiveMinimum: true format: double minimum: 0 type: number serum_bilirubin: description: Serum bilirubin value example: 5 exclusiveMinimum: true format: double minimum: 0 type: number serum_bilirubin_unit: description: Unit of serum bilirubin measurement enum: - mg/dL - µmol/L example: mg/dL type: string required: - prothrombin_time - control_time - serum_bilirubin - serum_bilirubin_unit type: object DFBodyResponse: additionalProperties: false properties: df: description: Calculated Discriminant Function value example: 42 format: double type: number metadata: $ref: "#/components/schemas/DFMetadata" description: Metadata about the calculation severity: description: Severity of alcoholic hepatitis based on DF value example: Severe type: string required: - df - severity - metadata type: object DFMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/DFBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object DICBodyRequest: additionalProperties: false properties: fibrin_marker: description: Elevation of fibrin-related marker enum: - no_increase - moderate_increase - strong_increase example: moderate_increase type: string fibrinogen: description: Fibrinogen level example: 1.5 exclusiveMinimum: true format: double minimum: 0 type: number fibrinogen_unit: description: Unit of fibrinogen measurement enum: - g/L - mg/dL example: g/L type: string platelet_count: description: Platelet count example: 75 exclusiveMinimum: true format: double minimum: 0 type: number platelet_count_unit: description: Unit of platelet count enum: - 10^9/L - 10^3/µL example: 10^9/L type: string prothrombin_time: description: Prothrombin time example: 18 exclusiveMinimum: true format: double minimum: 0 type: number prothrombin_time_unit: description: Unit of prothrombin time measurement enum: - seconds - INR example: seconds type: string required: - platelet_count - platelet_count_unit - fibrin_marker - fibrinogen - fibrinogen_unit - prothrombin_time - prothrombin_time_unit type: object DICBodyResponse: additionalProperties: false properties: comment: description: Assessment based on DIC Score example: High type: string metadata: $ref: "#/components/schemas/DICMetadata" description: Metadata about the calculation score: description: Calculated DIC Score example: 5 format: int64 type: integer required: - score - comment - metadata type: object DICMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/DICBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object DIPSSBodyRequest: additionalProperties: false properties: age: description: Age of the patient in years example: 65 exclusiveMinimum: true format: int64 minimum: 0 type: integer constitutional_symptoms: description: Presence of constitutional symptoms example: true type: boolean hemoglobin: description: Hemoglobin level example: 10 exclusiveMinimum: true format: double minimum: 0 type: number hemoglobin_unit: description: Unit of hemoglobin measurement enum: - g/dL - g/L example: g/dL type: string peripheral_blood_blasts: description: Percentage of peripheral blood blasts example: 1 format: double maximum: 100 minimum: 0 type: number wbc: description: White blood cell count example: 25 exclusiveMinimum: true format: double minimum: 0 type: number wbc_unit: description: Unit of white blood cell count measurement enum: - 10^9/L - K/µL example: 10^9/L type: string required: - age - hemoglobin - hemoglobin_unit - wbc - wbc_unit - peripheral_blood_blasts - constitutional_symptoms type: object DIPSSBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/DIPSSMetadata" description: Metadata about the calculation risk_group: description: Risk group based on DIPSS score example: Intermediate-2 type: string score: description: Calculated DIPSS score example: 2 format: int64 type: integer required: - score - risk_group - metadata type: object DIPSSMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/DIPSSBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object DeRitisBodyRequest: additionalProperties: false properties: alt: description: Alanine Aminotransferase (ALT) value example: 20 exclusiveMinimum: true format: double minimum: 0 type: number alt_unit: description: Unit of ALT measurement enum: - U/L - µkat/L example: U/L type: string ast: description: Aspartate Aminotransferase (AST) value example: 30 exclusiveMinimum: true format: double minimum: 0 type: number ast_unit: description: Unit of AST measurement enum: - U/L - µkat/L example: U/L type: string required: - ast - ast_unit - alt - alt_unit type: object DeRitisBodyResponse: additionalProperties: false properties: de_ritis_ratio: description: Calculated De Ritis Ratio example: 1.5 format: double type: number metadata: $ref: "#/components/schemas/DeRitisMetadata" description: Metadata about the calculation required: - de_ritis_ratio - metadata type: object DeRitisMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/DeRitisBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object EAGBodyRequest: additionalProperties: false properties: hba1c: description: HbA1c value example: 6.5 exclusiveMinimum: true format: double minimum: 0 type: number hba1c_unit: description: Unit of HbA1c measurement enum: - percentage - mmol/mol example: percentage type: string required: - hba1c - hba1c_unit type: object EAGBodyResponse: additionalProperties: false properties: eag: $ref: "#/components/schemas/EAGValue" description: Estimated Average Glucose in both units metadata: $ref: "#/components/schemas/EAGMetadata" description: Metadata about the calculation required: - eag - metadata type: object EAGMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/EAGBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object EAGValue: additionalProperties: false properties: mg_dl: description: Estimated Average Glucose in mg/dL example: 140 format: double type: number mmol_l: description: Estimated Average Glucose in mmol/L example: 7.8 format: double type: number required: - mg_dl - mmol_l type: object EGFRBodyRequest: additionalProperties: false properties: age: description: Age in years example: 50 format: int64 maximum: 150 minimum: 18 type: integer gender: description: Gender enum: - male - female example: female type: string serum_creatinine: description: Serum creatinine value example: 0.9 exclusiveMinimum: true format: double minimum: 0 type: number serum_creatinine_unit: description: Unit of serum creatinine measurement enum: - mg/dL - µmol/L example: mg/dL type: string serum_cystatin_c: description: Serum cystatin C value in mg/L (optional) example: 1 exclusiveMinimum: true format: double minimum: 0 type: number required: - age - gender - serum_creatinine - serum_creatinine_unit type: object EGFRBodyResponse: additionalProperties: false properties: category: description: CKD category based on eGFR value example: G2 type: string egfr: description: Estimated Glomerular Filtration Rate (mL/min/1.73m²) example: 92.5 format: double type: number equation: description: Equation used for eGFR calculation example: 2021 CKD-EPI creatinine type: string metadata: $ref: "#/components/schemas/EGFRMetadata" description: Metadata about the calculation required: - egfr - category - equation - metadata type: object EGFRMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/EGFRBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object EmoryModelTIPSBodyRequest: additionalProperties: false properties: alt: description: Alanine aminotransferase (ALT) level example: 120 exclusiveMinimum: true format: double minimum: 0 type: number alt_unit: description: Unit of ALT measurement enum: - IU/L - µkat/L example: IU/L type: string bilirubin: description: Bilirubin level example: 3.5 exclusiveMinimum: true format: double minimum: 0 type: number bilirubin_unit: description: Unit of bilirubin measurement enum: - mg/dL - µmol/L example: mg/dL type: string emergent_tips: description: Whether the TIPS procedure is emergent example: true type: boolean pre_tips_encephalopathy: description: Whether pre-TIPS encephalopathy is present example: true type: boolean required: - emergent_tips - alt - alt_unit - bilirubin - bilirubin_unit - pre_tips_encephalopathy type: object EmoryModelTIPSBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/EmoryModelTIPSMetadata" description: Metadata about the calculation risk_category: description: Risk category based on the calculated score example: High Risk type: string score: description: Calculated Emory Model (TIPS) score example: 4 format: int64 type: integer required: - score - risk_category - metadata type: object EmoryModelTIPSMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/EmoryModelTIPSBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object ErrorDetail: additionalProperties: false properties: location: description: Where the error occurred, e.g. 'body.items[3].tags' or 'path.thing-id' type: string message: description: Error message text type: string value: description: The value at the given location type: object ErrorModel: additionalProperties: false properties: detail: description: A human-readable explanation specific to this occurrence of the problem. example: Property foo is required but is missing. type: string errors: description: Optional list of individual error details items: $ref: "#/components/schemas/ErrorDetail" nullable: true type: array instance: description: A URI reference that identifies the specific occurrence of the problem. example: https://example.com/error-log/abc123 format: uri type: string status: description: HTTP status code example: 400 format: int64 type: integer title: description: A short, human-readable summary of the problem type. This value should not change between occurrences of the error. example: Bad Request type: string type: default: about:blank description: A URI reference to human-readable documentation for the error. example: https://example.com/errors/example format: uri type: string type: object FARBodyRequest: additionalProperties: false properties: albumin: description: Albumin value example: 4 exclusiveMinimum: true format: double minimum: 0 type: number albumin_unit: description: Unit of albumin measurement enum: - g/L - g/dL example: g/dL type: string fibrinogen: description: Fibrinogen value example: 3.5 exclusiveMinimum: true format: double minimum: 0 type: number fibrinogen_unit: description: Unit of fibrinogen measurement enum: - g/L - mg/dL example: g/L type: string required: - fibrinogen - fibrinogen_unit - albumin - albumin_unit type: object FARBodyResponse: additionalProperties: false properties: far: description: Calculated Fibrinogen-to-Albumin Ratio example: 0.875 format: double type: number metadata: $ref: "#/components/schemas/FARMetadata" description: Metadata about the calculation required: - far - metadata type: object FARMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/FARBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object FENaBodyRequest: additionalProperties: false properties: serum_creatinine: description: Serum creatinine value example: 1.2 exclusiveMinimum: true format: double minimum: 0 type: number serum_creatinine_unit: description: Unit of serum creatinine measurement enum: - mg/dL - µmol/L example: mg/dL type: string serum_sodium: description: Serum sodium value example: 140 exclusiveMinimum: true format: double minimum: 0 type: number serum_sodium_unit: description: Unit of serum sodium measurement enum: - mmol/L - mEq/L example: mmol/L type: string urine_creatinine: description: Urine creatinine value example: 100 exclusiveMinimum: true format: double minimum: 0 type: number urine_creatinine_unit: description: Unit of urine creatinine measurement enum: - mg/dL - µmol/L example: mg/dL type: string urine_sodium: description: Urine sodium value example: 80 exclusiveMinimum: true format: double minimum: 0 type: number urine_sodium_unit: description: Unit of urine sodium measurement enum: - mmol/L - mEq/L example: mmol/L type: string required: - serum_sodium - serum_sodium_unit - urine_sodium - urine_sodium_unit - serum_creatinine - serum_creatinine_unit - urine_creatinine - urine_creatinine_unit type: object FENaBodyResponse: additionalProperties: false properties: fena: description: Calculated Fractional Excretion of Sodium (%) example: 1.2 format: double type: number metadata: $ref: "#/components/schemas/FENaMetadata" description: Metadata about the calculation required: - fena - metadata type: object FENaMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/FENaBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object FIB4BodyRequest: additionalProperties: false properties: age: description: Age in years example: 50 exclusiveMinimum: true format: int64 minimum: 0 type: integer alt: description: Alanine aminotransferase (ALT) value example: 35 exclusiveMinimum: true format: double minimum: 0 type: number alt_unit: description: Unit of ALT measurement enum: - U/L - µkat/L example: U/L type: string ast: description: Aspartate aminotransferase (AST) value example: 40 exclusiveMinimum: true format: double minimum: 0 type: number ast_unit: description: Unit of AST measurement enum: - U/L - µkat/L example: U/L type: string platelet_count: description: Platelet count example: 200 exclusiveMinimum: true format: double minimum: 0 type: number platelet_count_unit: description: Unit of platelet count measurement enum: - 10^9/L - 10^3/µL example: 10^9/L type: string required: - age - ast - ast_unit - alt - alt_unit - platelet_count - platelet_count_unit type: object FIB4BodyResponse: additionalProperties: false properties: fib4_score: description: Calculated FIB-4 score example: 1.45 format: double type: number metadata: $ref: "#/components/schemas/FIB4Metadata" description: Metadata about the calculation required: - fib4_score - metadata type: object FIB4Metadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/FIB4BodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object FLIBodyRequest: additionalProperties: false properties: bmi: description: Body Mass Index (BMI) example: 25 exclusiveMinimum: true format: double minimum: 0 type: number ggt: description: Gamma-glutamyl transferase (GGT) value example: 30 exclusiveMinimum: true format: double minimum: 0 type: number ggt_unit: description: Unit of GGT measurement enum: - U/L - µkat/L example: U/L type: string triglycerides: description: Triglycerides value example: 150 exclusiveMinimum: true format: double minimum: 0 type: number triglycerides_unit: description: Unit of triglycerides measurement enum: - mg/dL - mmol/L example: mg/dL type: string waist_circumference: description: Waist circumference example: 90 exclusiveMinimum: true format: double minimum: 0 type: number waist_circumference_unit: description: Unit of waist circumference measurement enum: - cm - in example: cm type: string required: - bmi - waist_circumference - waist_circumference_unit - triglycerides - triglycerides_unit - ggt - ggt_unit type: object FLIBodyResponse: additionalProperties: false properties: fli: description: Fatty Liver Index example: 60.5 format: double type: number metadata: $ref: "#/components/schemas/FLIMetadata" description: Metadata about the calculation risk: description: Risk category based on FLI value example: Intermediate type: string required: - fli - risk - metadata type: object FLIMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/FLIBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object FLIPIBodyRequest: additionalProperties: false properties: age: description: Age of the patient in years example: 60 exclusiveMinimum: true format: int64 minimum: 0 type: integer ann_arbor_stage: description: Ann Arbor stage enum: - 1 - 2 - 3 - 4 example: 3 format: int64 type: integer hemoglobin: description: Hemoglobin level example: 12 exclusiveMinimum: true format: double minimum: 0 type: number hemoglobin_unit: description: Unit of hemoglobin measurement enum: - g/dL - g/L example: g/dL type: string ldh: description: Lactate dehydrogenase (LDH) level example: 300 exclusiveMinimum: true format: double minimum: 0 type: number ldh_unit: description: Unit of LDH measurement enum: - U/L - µkat/L example: U/L type: string ldh_upper_limit: description: Laboratory upper limit of normal for LDH example: 200 exclusiveMinimum: true format: double minimum: 0 type: number ldh_upper_limit_unit: description: Unit of LDH upper limit measurement enum: - U/L - µkat/L example: U/L type: string nodal_sites: description: Number of nodal sites example: 5 format: int64 minimum: 0 type: integer required: - age - ann_arbor_stage - hemoglobin - hemoglobin_unit - ldh - ldh_unit - ldh_upper_limit - ldh_upper_limit_unit - nodal_sites type: object FLIPIBodyResponse: additionalProperties: false properties: flipi_score: description: Calculated FLIPI score example: 3 format: int64 type: integer metadata: $ref: "#/components/schemas/FLIPIMetadata" description: Metadata about the calculation risk_group: description: Risk group based on FLIPI score example: High risk type: string required: - flipi_score - risk_group - metadata type: object FLIPIMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/FLIPIBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object FWCBodyRequest: additionalProperties: false properties: plasma_osmolality: description: Plasma osmolality example: 290 exclusiveMinimum: true format: double minimum: 0 type: number plasma_osmolality_unit: description: Unit of plasma osmolality measurement enum: - mOsm/kg - mmol/kg example: mOsm/kg type: string urine_flow_rate: description: Urine flow rate example: 1.5 exclusiveMinimum: true format: double minimum: 0 type: number urine_flow_rate_unit: description: Unit of urine flow rate measurement enum: - mL/min - L/day example: mL/min type: string urine_osmolality: description: Urine osmolality example: 600 exclusiveMinimum: true format: double minimum: 0 type: number urine_osmolality_unit: description: Unit of urine osmolality measurement enum: - mOsm/kg - mmol/kg example: mOsm/kg type: string required: - urine_flow_rate - urine_flow_rate_unit - urine_osmolality - urine_osmolality_unit - plasma_osmolality - plasma_osmolality_unit type: object FWCBodyResponse: additionalProperties: false properties: free_water_clearance: description: Calculated Free Water Clearance in mL/min example: -0.62 format: double type: number interpretation: description: Interpretation of the Free Water Clearance result example: Negative free water clearance indicates water retention type: string metadata: $ref: "#/components/schemas/FWCMetadata" description: Metadata about the calculation required: - free_water_clearance - interpretation - metadata type: object FWCMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/FWCBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object FraminghamCVDBodyRequest: additionalProperties: false properties: age: description: Age in years example: 50 format: int64 maximum: 74 minimum: 30 type: integer diabetes: description: Whether the person has diabetes example: false type: boolean gender: description: Gender enum: - male - female example: male type: string hdl_cholesterol: description: HDL cholesterol value example: 50 exclusiveMinimum: true format: double minimum: 0 type: number hdl_cholesterol_unit: description: Unit of HDL cholesterol measurement enum: - mg/dL - mmol/L example: mg/dL type: string is_on_blood_pressure_medication: description: Whether the person is on blood pressure medication example: false type: boolean is_smoker: description: Whether the person is a smoker example: false type: boolean systolic_blood_pressure: description: Systolic blood pressure value in mmHg example: 120 exclusiveMinimum: true format: double minimum: 0 type: number total_cholesterol: description: Total cholesterol value example: 200 exclusiveMinimum: true format: double minimum: 0 type: number total_cholesterol_unit: description: Unit of total cholesterol measurement enum: - mg/dL - mmol/L example: mg/dL type: string required: - age - gender - total_cholesterol - total_cholesterol_unit - hdl_cholesterol - hdl_cholesterol_unit - systolic_blood_pressure - is_on_blood_pressure_medication - is_smoker - diabetes type: object FraminghamCVDBodyResponse: additionalProperties: false properties: heart_age_from_points: description: Heart age/vascular age in years example: "55" type: string metadata: $ref: "#/components/schemas/FraminghamCVDMetadata" description: Metadata about the calculation point_total: description: Total points from the scoring system example: 15 format: int64 type: integer ten_year_cvd_risk_cox_model: description: 10-year cardiovascular disease risk (%) example: 10.5 format: double type: number ten_year_cvd_risk_from_points: description: 10-year CVD risk estimated from points (%) example: "11.2" type: string required: - point_total - ten_year_cvd_risk_from_points - heart_age_from_points - ten_year_cvd_risk_cox_model - metadata type: object FraminghamCVDMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/FraminghamCVDBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object GALADBodyRequest: additionalProperties: false properties: afp: description: AFP value example: 20 exclusiveMinimum: true format: double minimum: 0 type: number afp_l3_percent: description: AFP-L3 value example: 10 format: double minimum: 0 type: number afp_unit: description: Unit of AFP measurement enum: - ng/mL - IU/mL - kIU/L example: ng/mL type: string age: description: Age in years example: 60 exclusiveMinimum: true format: double minimum: 0 type: number dcp: description: DCP value example: 150 exclusiveMinimum: true format: double minimum: 0 type: number dcp_unit: description: Unit of DCP measurement enum: - ng/mL - mAU/mL example: ng/mL type: string gender: description: Gender enum: - male - female example: male type: string required: - gender - age - afp - afp_unit - afp_l3_percent - dcp - dcp_unit type: object GALADBodyResponse: additionalProperties: false properties: galad_score: description: Calculated GALAD score example: 2.5 format: double type: number metadata: $ref: "#/components/schemas/GALADMetadata" description: Metadata about the calculation required: - galad_score - metadata type: object GALADMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/GALADBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object GPRBodyRequest: additionalProperties: false properties: ggt: description: Gamma-Glutamyl Transferase (GGT) value example: 75 exclusiveMinimum: true format: double minimum: 0 type: number ggt_unit: description: Unit of GGT measurement enum: - U/L - µkat/L example: U/L type: string platelet_count: description: Platelet Count value example: 200 exclusiveMinimum: true format: double minimum: 0 type: number platelet_count_unit: description: Unit of Platelet Count measurement enum: - 10^9/L - 10^3/µL example: 10^9/L type: string uln_ggt: description: Upper Limit of Normal GGT value example: 50 exclusiveMinimum: true format: double minimum: 0 type: number uln_ggt_unit: description: Unit of Upper Limit of Normal GGT measurement enum: - U/L - µkat/L example: U/L type: string required: - ggt - ggt_unit - uln_ggt - uln_ggt_unit - platelet_count - platelet_count_unit type: object GPRBodyResponse: additionalProperties: false properties: gpr: description: Calculated Gamma-Glutamyl Transferase to Platelet Ratio example: 0.75 format: double type: number metadata: $ref: "#/components/schemas/GPRMetadata" description: Metadata about the calculation required: - gpr - metadata type: object GPRMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/GPRBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object GanzoniBodyRequest: additionalProperties: false properties: hemoglobin: description: Current hemoglobin level example: 10 exclusiveMinimum: true format: double minimum: 0 type: number hemoglobin_unit: description: Unit of hemoglobin measurement enum: - g/dL - g/L example: g/dL type: string storage_iron: description: "Storage iron (optional, default: 500 mg)" example: 500 format: double minimum: 0 type: number target_hemoglobin: description: Target hemoglobin level example: 14 exclusiveMinimum: true format: double minimum: 0 type: number target_hemoglobin_unit: description: Unit of target hemoglobin measurement enum: - g/dL - g/L example: g/dL type: string weight: description: Body weight example: 70 exclusiveMinimum: true format: double minimum: 0 type: number weight_unit: description: Unit of body weight measurement enum: - kg - lb example: kg type: string required: - weight - weight_unit - hemoglobin - hemoglobin_unit - target_hemoglobin - target_hemoglobin_unit type: object GanzoniBodyResponse: additionalProperties: false properties: iron_deficit: $ref: "#/components/schemas/IronDeficitValues" description: Calculated iron deficit metadata: $ref: "#/components/schemas/GanzoniMetadata" description: Metadata about the calculation required: - iron_deficit - metadata type: object GanzoniMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/GanzoniBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object HOMAIRBodyRequest: additionalProperties: false properties: fasting_glucose: description: Fasting glucose value example: 95 exclusiveMinimum: true format: double minimum: 0 type: number fasting_glucose_unit: description: Unit of fasting glucose measurement enum: - mg/dL - mmol/L - mIU/L example: mg/dL type: string fasting_insulin: description: Fasting insulin value example: 10 exclusiveMinimum: true format: double minimum: 0 type: number fasting_insulin_unit: description: Unit of fasting insulin measurement enum: - µIU/mL - pmol/L - mIU/L example: µIU/mL type: string required: - fasting_glucose - fasting_glucose_unit - fasting_insulin - fasting_insulin_unit type: object HOMAIRBodyResponse: additionalProperties: false properties: homa_ir: description: Calculated HOMA-IR value example: 2.35 format: double type: number metadata: $ref: "#/components/schemas/HOMAIRMetadata" description: Metadata about the calculation required: - homa_ir - metadata type: object HOMAIRMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/HOMAIRBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object IPSSWMBodyRequest: additionalProperties: false properties: age: description: Age of the patient in years example: 65 exclusiveMinimum: true format: int64 minimum: 0 type: integer beta2_microglobulin: description: Beta-2 microglobulin value example: 3.5 exclusiveMinimum: true format: double minimum: 0 type: number beta2_microglobulin_unit: description: Unit of beta-2 microglobulin measurement enum: - mg/L - µg/L - µg/mL example: mg/L type: string hemoglobin: description: Hemoglobin value example: 11.5 exclusiveMinimum: true format: double minimum: 0 type: number hemoglobin_unit: description: Unit of hemoglobin measurement enum: - g/dL - g/L example: g/dL type: string monoclonal_igm: description: Monoclonal IgM value example: 40 exclusiveMinimum: true format: double minimum: 0 type: number monoclonal_igm_unit: description: Unit of monoclonal IgM measurement enum: - g/L - g/dL example: g/L type: string platelet_count: description: Platelet count example: 150 exclusiveMinimum: true format: double minimum: 0 type: number platelet_count_unit: description: Unit of platelet count enum: - 10^9/L - 10^3/µL example: 10^9/L type: string required: - age - hemoglobin - hemoglobin_unit - platelet_count - platelet_count_unit - beta2_microglobulin - beta2_microglobulin_unit - monoclonal_igm - monoclonal_igm_unit type: object IPSSWMBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/IPSSWMMetadata" description: Metadata about the calculation risk_group: description: Risk group based on IPSSWM score example: Intermediate type: string score: description: IPSSWM score example: 2 format: int64 type: integer required: - score - risk_group - metadata type: object IPSSWMMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/IPSSWMBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object IronDeficitValues: additionalProperties: false properties: g: description: Iron deficit in grams example: 1 format: double type: number mg: description: Iron deficit in milligrams example: 1000 format: double type: number required: - mg - g type: object LAPBodyRequest: additionalProperties: false properties: gender: description: Gender enum: - male - female example: female type: string triglycerides: description: Triglycerides value example: 150 exclusiveMinimum: true format: double minimum: 0 type: number triglycerides_unit: description: Unit of triglycerides measurement enum: - mg/dL - mmol/L example: mg/dL type: string waist_circumference: description: Waist circumference example: 80 exclusiveMinimum: true format: double minimum: 0 type: number waist_circumference_unit: description: Unit of waist circumference measurement enum: - cm - in example: cm type: string required: - gender - waist_circumference - waist_circumference_unit - triglycerides - triglycerides_unit type: object LAPBodyResponse: additionalProperties: false properties: lap: description: Calculated Lipid Accumulation Product example: 47.6 format: double type: number metadata: $ref: "#/components/schemas/LAPMetadata" description: Metadata about the calculation required: - lap - metadata type: object LAPMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/LAPBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object LDLCalculatorBodyRequest: additionalProperties: false properties: hdl_cholesterol: description: HDL cholesterol value example: 50 exclusiveMinimum: true format: double minimum: 0 type: number hdl_cholesterol_unit: description: Unit of HDL cholesterol measurement enum: - mg/dL - mmol/L example: mg/dL type: string total_cholesterol: description: Total cholesterol value example: 200 exclusiveMinimum: true format: double minimum: 0 type: number total_cholesterol_unit: description: Unit of total cholesterol measurement enum: - mg/dL - mmol/L example: mg/dL type: string triglycerides: description: Triglycerides value example: 150 exclusiveMinimum: true format: double minimum: 0 type: number triglycerides_unit: description: Unit of triglycerides measurement enum: - mg/dL - mmol/L example: mg/dL type: string required: - total_cholesterol - total_cholesterol_unit - hdl_cholesterol - hdl_cholesterol_unit - triglycerides - triglycerides_unit type: object LDLCalculatorBodyResponse: additionalProperties: false properties: ldl: $ref: "#/components/schemas/LDLValue" description: Calculated LDL cholesterol values metadata: $ref: "#/components/schemas/LDLCalculatorMetadata" description: Metadata about the calculation required: - ldl - metadata type: object LDLCalculatorMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/LDLCalculatorBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object LDLValue: additionalProperties: false properties: mg_dl: description: LDL cholesterol in mg/dL example: 100 format: double type: number mmol_l: description: LDL cholesterol in mmol/L example: 2.59 format: double type: number required: - mg_dl - mmol_l type: object LMRBodyRequest: additionalProperties: false properties: lymphocyte_count: description: Lymphocyte count example: 2 exclusiveMinimum: true format: double minimum: 0 type: number lymphocyte_count_unit: description: Unit of lymphocyte count enum: - 10^9/L - cells/µL example: 10^9/L type: string monocyte_count: description: Monocyte count example: 0.5 exclusiveMinimum: true format: double minimum: 0 type: number monocyte_count_unit: description: Unit of monocyte count enum: - 10^9/L - cells/µL example: 10^9/L type: string required: - lymphocyte_count - lymphocyte_count_unit - monocyte_count - monocyte_count_unit type: object LMRBodyResponse: additionalProperties: false properties: lmr: description: Calculated Lymphocyte-to-Monocyte Ratio example: 4 format: double type: number metadata: $ref: "#/components/schemas/LMRMetadata" description: Metadata about the calculation required: - lmr - metadata type: object LMRMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/LMRBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object MGPSBodyRequest: additionalProperties: false properties: albumin: description: Albumin value example: 35 exclusiveMinimum: true format: double minimum: 0 type: number albumin_unit: description: Unit of albumin measurement enum: - g/L - g/dL example: g/L type: string c_reactive_protein: description: C-reactive protein (CRP) value example: 15 exclusiveMinimum: true format: double minimum: 0 type: number c_reactive_protein_unit: description: Unit of CRP measurement enum: - mg/L - mg/dL example: mg/L type: string required: - c_reactive_protein - c_reactive_protein_unit - albumin - albumin_unit type: object MGPSBodyResponse: additionalProperties: false properties: interpretation: description: Interpretation of the mGPS score example: Intermediate risk type: string metadata: $ref: "#/components/schemas/MGPSMetadata" description: Metadata about the calculation score: description: Modified Glasgow Prognostic Score example: 1 format: int64 type: integer required: - score - interpretation - metadata type: object MGPSMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/MGPSBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object MHRBodyRequest: additionalProperties: false properties: hdl_cholesterol: description: HDL cholesterol value example: 1.2 exclusiveMinimum: true format: double minimum: 0 type: number hdl_cholesterol_unit: description: Unit of HDL cholesterol measurement enum: - mmol/L - mg/dL example: mmol/L type: string monocyte_count: description: Monocyte count value example: 0.5 exclusiveMinimum: true format: double minimum: 0 type: number monocyte_count_unit: description: Unit of monocyte count measurement enum: - 10^9/L - cells/µL example: 10^9/L type: string required: - monocyte_count - monocyte_count_unit - hdl_cholesterol - hdl_cholesterol_unit type: object MHRBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/MHRMetadata" description: Metadata about the calculation mhr: description: Monocyte-to-HDL Ratio example: 0.417 format: double type: number required: - mhr - metadata type: object MHRMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/MHRBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object MMPBodyRequest: additionalProperties: false properties: albumin: description: Serum albumin value example: 3.5 exclusiveMinimum: true format: double minimum: 0 type: number albumin_unit: description: Unit of serum albumin measurement enum: - g/dL - g/L example: g/dL type: string beta2_microglobulin: description: Serum β2-microglobulin value example: 3.5 exclusiveMinimum: true format: double minimum: 0 type: number beta2_microglobulin_unit: description: Unit of serum β2-microglobulin measurement enum: - mg/L - µg/L - µg/mL example: mg/L type: string required: - beta2_microglobulin - beta2_microglobulin_unit - albumin - albumin_unit type: object MMPBodyResponse: additionalProperties: false properties: median_survival: description: Median survival in months example: 44 format: int64 type: integer metadata: $ref: "#/components/schemas/MMPMetadata" description: Metadata about the calculation stage: description: ISS stage (1, 2, or 3) example: 2 format: int64 type: integer required: - stage - median_survival - metadata type: object MMPMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/MMPBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object MetSBodyRequest: additionalProperties: false properties: blood_pressure_diastolic: description: Diastolic blood pressure example: 85 exclusiveMinimum: true format: double minimum: 0 type: number blood_pressure_systolic: description: Systolic blood pressure example: 130 exclusiveMinimum: true format: double minimum: 0 type: number fasting_glucose: description: Fasting glucose level example: 100 exclusiveMinimum: true format: double minimum: 0 type: number fasting_glucose_unit: description: Unit of fasting glucose measurement enum: - mg/dL - mmol/L example: mg/dL type: string gender: description: Gender of the person enum: - male - female example: male type: string hdl_cholesterol: description: HDL cholesterol level example: 40 exclusiveMinimum: true format: double minimum: 0 type: number hdl_cholesterol_unit: description: Unit of HDL cholesterol measurement enum: - mg/dL - mmol/L example: mg/dL type: string triglycerides: description: Triglycerides level example: 150 exclusiveMinimum: true format: double minimum: 0 type: number triglycerides_unit: description: Unit of triglycerides measurement enum: - mg/dL - mmol/L example: mg/dL type: string waist_circumference: description: Waist circumference example: 90 exclusiveMinimum: true format: double minimum: 0 type: number waist_circumference_unit: description: Unit of waist circumference measurement enum: - cm - in example: cm type: string required: - gender - waist_circumference - waist_circumference_unit - triglycerides - triglycerides_unit - hdl_cholesterol - hdl_cholesterol_unit - blood_pressure_systolic - blood_pressure_diastolic - fasting_glucose - fasting_glucose_unit type: object MetSBodyResponse: additionalProperties: false properties: criteria_met: description: List of MetS criteria met example: - Elevated Waist Circumference - Elevated Triglycerides items: type: string nullable: true type: array has_metabolic_syndrome: description: Whether the person has Metabolic Syndrome example: true type: boolean metadata: $ref: "#/components/schemas/MetSMetadata" description: Metadata about the calculation required: - has_metabolic_syndrome - criteria_met - metadata type: object MetSMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/MetSBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object ModifiedHendersonBodyRequest: additionalProperties: false properties: hco3: description: Bicarbonate (HCO3-) concentration example: 24 exclusiveMinimum: true format: double minimum: 0 type: number hco3_unit: description: Unit of HCO3- measurement enum: - mEq/L - mmol/L example: mEq/L type: string pco2: description: Partial pressure of carbon dioxide (PCO2) example: 40 exclusiveMinimum: true format: double minimum: 0 type: number pco2_unit: description: Unit of PCO2 measurement enum: - mmHg - kPa example: mmHg type: string required: - pco2 - pco2_unit - hco3 - hco3_unit type: object ModifiedHendersonBodyResponse: additionalProperties: false properties: calculated_ph: description: Calculated pH example: 7.4 format: double type: number hydrogen_ion_concentration: description: Calculated hydrogen ion concentration [H+] in nmol/L example: 40 format: double type: number metadata: $ref: "#/components/schemas/ModifiedHendersonMetadata" description: Metadata about the calculation required: - hydrogen_ion_concentration - calculated_ph - metadata type: object ModifiedHendersonMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/ModifiedHendersonBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object NAFLDBodyRequest: additionalProperties: false properties: age: description: Age in years example: 50 exclusiveMinimum: true format: int64 minimum: 0 type: integer albumin: description: Albumin value example: 4 exclusiveMinimum: true format: double minimum: 0 type: number albumin_unit: description: Unit of albumin measurement enum: - g/dL - g/L example: g/dL type: string alt: description: Alanine Aminotransferase (ALT) value example: 50 exclusiveMinimum: true format: double minimum: 0 type: number alt_unit: description: Unit of ALT measurement enum: - U/L - µkat/L example: U/L type: string ast: description: Aspartate Aminotransferase (AST) value example: 40 exclusiveMinimum: true format: double minimum: 0 type: number ast_unit: description: Unit of AST measurement enum: - U/L - µkat/L example: U/L type: string bmi: description: Body Mass Index (BMI) example: 28.5 exclusiveMinimum: true format: double minimum: 0 type: number diabetes: description: Presence of diabetes or impaired fasting glucose example: false type: boolean platelets: description: Platelet count example: 200 exclusiveMinimum: true format: double minimum: 0 type: number platelets_unit: description: Unit of platelet count measurement enum: - 10^9/L - 10^3/µL example: 10^9/L type: string required: - age - bmi - diabetes - ast - ast_unit - alt - alt_unit - platelets - platelets_unit - albumin - albumin_unit type: object NAFLDBodyResponse: additionalProperties: false properties: interpretation: description: Interpretation of the NAFLD Fibrosis Score example: Low risk of advanced fibrosis type: string metadata: $ref: "#/components/schemas/NAFLDMetadata" description: Metadata about the calculation score: description: NAFLD Fibrosis Score example: -1.455 format: double type: number required: - score - interpretation - metadata type: object NAFLDMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/NAFLDBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object NARBodyRequest: additionalProperties: false properties: albumin: description: Albumin value example: 4 exclusiveMinimum: true format: double minimum: 0 type: number albumin_unit: description: Unit of albumin measurement enum: - g/dL - g/L example: g/dL type: string neutrophil_count: description: Neutrophil count value example: 4.5 exclusiveMinimum: true format: double minimum: 0 type: number neutrophil_count_unit: description: Unit of neutrophil count measurement enum: - 10^9/L - cells/µL example: 10^9/L type: string required: - neutrophil_count - neutrophil_count_unit - albumin - albumin_unit type: object NARBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/NARMetadata" description: Metadata about the calculation nar: description: Calculated Neutrophil-to-Albumin Ratio example: 1.125 format: double type: number required: - nar - metadata type: object NARMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/NARBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object OsmolalGapBodyRequest: additionalProperties: false properties: glucose: description: Glucose concentration example: 100 exclusiveMinimum: true format: double minimum: 0 type: number glucose_unit: description: Unit of glucose concentration enum: - mg/dL - mmol/L example: mg/dL type: string measured_osmolality: description: Measured osmolality value example: 290 exclusiveMinimum: true format: double minimum: 0 type: number measured_osmolality_unit: description: Unit of measured osmolality enum: - mOsm/kg - mmol/kg example: mOsm/kg type: string potassium: description: Potassium (K) concentration example: 4.5 exclusiveMinimum: true format: double minimum: 0 type: number potassium_unit: description: Unit of potassium concentration enum: - mEq/L - mmol/L example: mEq/L type: string sodium: description: Sodium (Na) concentration example: 135 exclusiveMinimum: true format: double minimum: 0 type: number sodium_unit: description: Unit of sodium concentration enum: - mEq/L - mmol/L example: mEq/L type: string urea: description: Urea concentration example: 15 exclusiveMinimum: true format: double minimum: 0 type: number urea_unit: description: Unit of urea concentration enum: - mg/dL - mmol/L example: mg/dL type: string required: - measured_osmolality - measured_osmolality_unit - sodium - sodium_unit - potassium - potassium_unit - glucose - glucose_unit - urea - urea_unit type: object OsmolalGapBodyResponse: additionalProperties: false properties: calculated_osmolality: description: Calculated Serum Osmolality example: 280 format: double type: number metadata: $ref: "#/components/schemas/OsmolalGapMetadata" description: Metadata about the calculation osmolal_gap: description: Calculated Osmolal Gap example: 10 format: double type: number required: - osmolal_gap - calculated_osmolality - metadata type: object OsmolalGapMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/OsmolalGapBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object PNIBodyRequest: additionalProperties: false properties: serum_albumin: description: Serum albumin value example: 3.5 exclusiveMinimum: true format: double minimum: 0 type: number serum_albumin_unit: description: Unit of serum albumin measurement enum: - g/dL - g/L example: g/dL type: string total_lymphocyte_count: description: Total lymphocyte count example: 1500 exclusiveMinimum: true format: double minimum: 0 type: number total_lymphocyte_count_unit: description: Unit of total lymphocyte count measurement enum: - cells/µL - cells/mm^3 - 10^9/L example: cells/µL type: string required: - serum_albumin - serum_albumin_unit - total_lymphocyte_count - total_lymphocyte_count_unit type: object PNIBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/PNIMetadata" description: Metadata about the calculation pni: description: Calculated Prognostic Nutritional Index example: 45.5 format: double type: number required: - pni - metadata type: object PNIMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/PNIBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object QUICKIBodyRequest: additionalProperties: false properties: fasting_glucose: description: Fasting glucose value example: 95 exclusiveMinimum: true format: double minimum: 0 type: number fasting_glucose_unit: description: Unit of fasting glucose measurement enum: - mg/dL - mmol/L - mIU/L example: mg/dL type: string fasting_insulin: description: Fasting insulin value example: 10 exclusiveMinimum: true format: double minimum: 0 type: number fasting_insulin_unit: description: Unit of fasting insulin measurement enum: - µIU/mL - pmol/L - mIU/L example: µIU/mL type: string required: - fasting_glucose - fasting_glucose_unit - fasting_insulin - fasting_insulin_unit type: object QUICKIBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/QUICKIMetadata" description: Metadata about the calculation quicki: description: Calculated QUICKI value example: 0.34 format: double type: number required: - quicki - metadata type: object QUICKIMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/QUICKIBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object RPIBodyRequest: additionalProperties: false properties: hematocrit: description: Hematocrit value example: 35 exclusiveMinimum: true format: double minimum: 0 type: number hematocrit_unit: description: Unit of hematocrit measurement enum: - percent - L/L example: percent type: string normal_hematocrit: description: Normal hematocrit value (optional) example: 45 exclusiveMinimum: true format: double minimum: 0 type: number normal_hematocrit_unit: description: Unit of normal hematocrit measurement (optional) enum: - percent - L/L example: percent type: string reticulocyte_percentage: description: Reticulocyte percentage example: 2.5 exclusiveMinimum: true format: double maximum: 100 minimum: 0 type: number required: - reticulocyte_percentage - hematocrit - hematocrit_unit type: object RPIBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/RPIMetadata" description: Metadata about the calculation rpi: description: Calculated Reticulocyte Production Index example: 1.5 format: double type: number required: - rpi - metadata type: object RPIMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/RPIBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object RPRBodyRequest: additionalProperties: false properties: platelet_count: description: Platelet Count value example: 200 exclusiveMinimum: true format: double minimum: 0 type: number platelet_count_unit: description: Unit of Platelet Count measurement enum: - 10^9/L - 10^3/µL example: 10^9/L type: string rdw: description: Red Cell Distribution Width value example: 14.5 exclusiveMinimum: true format: double minimum: 0 type: number required: - rdw - platelet_count - platelet_count_unit type: object RPRBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/RPRMetadata" description: Metadata about the calculation rpr: description: Red Cell Distribution Width to Platelet Ratio example: 0.0725 format: double type: number required: - rpr - metadata type: object RPRMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/RPRBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object RemnantCholesterolBodyRequest: additionalProperties: false properties: hdl_cholesterol: description: HDL cholesterol value example: 50 exclusiveMinimum: true format: double minimum: 0 type: number hdl_cholesterol_unit: description: Unit of HDL cholesterol measurement enum: - mg/dL - mmol/L example: mg/dL type: string ldl_cholesterol: description: LDL cholesterol value example: 100 exclusiveMinimum: true format: double minimum: 0 type: number ldl_cholesterol_unit: description: Unit of LDL cholesterol measurement enum: - mg/dL - mmol/L example: mg/dL type: string total_cholesterol: description: Total cholesterol value example: 200 exclusiveMinimum: true format: double minimum: 0 type: number total_cholesterol_unit: description: Unit of total cholesterol measurement enum: - mg/dL - mmol/L example: mg/dL type: string required: - total_cholesterol - total_cholesterol_unit - hdl_cholesterol - hdl_cholesterol_unit - ldl_cholesterol - ldl_cholesterol_unit type: object RemnantCholesterolBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/RemnantCholesterolMetadata" description: Metadata about the calculation remnant_cholesterol: $ref: "#/components/schemas/RemnantCholesterolValue" description: Calculated remnant cholesterol values required: - remnant_cholesterol - metadata type: object RemnantCholesterolMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/RemnantCholesterolBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object RemnantCholesterolValue: additionalProperties: false properties: mg_dl: description: Remnant cholesterol in mg/dL example: 30 format: double type: number mmol_l: description: Remnant cholesterol in mmol/L example: 0.78 format: double type: number required: - mg_dl - mmol_l type: object ReynoldsCADRiskMenBodyRequest: additionalProperties: false properties: age: description: Age in years example: 50 format: int64 maximum: 80 minimum: 30 type: integer family_history_mi: description: Family history of myocardial infarction before age 60 example: false type: boolean hdl_cholesterol: description: HDL cholesterol value example: 50 exclusiveMinimum: true format: double minimum: 0 type: number hdl_cholesterol_unit: description: Unit of HDL cholesterol measurement enum: - mg/dL - mmol/L example: mg/dL type: string high_sensitivity_crp: description: High-sensitivity C-reactive protein value example: 1.5 exclusiveMinimum: true format: double minimum: 0 type: number high_sensitivity_crp_unit: description: Unit of high-sensitivity CRP measurement enum: - mg/L - mg/dL example: mg/L type: string smoker: description: Whether the person is a smoker example: false type: boolean systolic_blood_pressure: description: Systolic blood pressure example: 120 exclusiveMinimum: true format: double minimum: 0 type: number total_cholesterol: description: Total cholesterol value example: 200 exclusiveMinimum: true format: double minimum: 0 type: number total_cholesterol_unit: description: Unit of total cholesterol measurement enum: - mg/dL - mmol/L example: mg/dL type: string required: - age - systolic_blood_pressure - total_cholesterol - total_cholesterol_unit - hdl_cholesterol - hdl_cholesterol_unit - high_sensitivity_crp - high_sensitivity_crp_unit - smoker - family_history_mi type: object ReynoldsCADRiskMenBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/ReynoldsCADRiskMenMetadata" description: Metadata about the calculation risk_level: description: Risk level classification example: Low type: string ten_year_risk: description: 10-year risk of cardiovascular disease (%) example: 5.2 format: double type: number required: - ten_year_risk - risk_level - metadata type: object ReynoldsCADRiskMenMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/ReynoldsCADRiskMenBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object ReynoldsCADRiskWomenBodyRequest: additionalProperties: false properties: age: description: Age in years example: 50 format: int64 maximum: 80 minimum: 30 type: integer family_history_mi: description: Family history of myocardial infarction before age 60 example: false type: boolean hdl_cholesterol: description: HDL cholesterol value example: 50 exclusiveMinimum: true format: double minimum: 0 type: number hdl_cholesterol_unit: description: Unit of HDL cholesterol measurement enum: - mg/dL - mmol/L example: mg/dL type: string hemoglobin_a1c: description: Hemoglobin A1c value (optional, required for diabetic patients), in % example: 5.7 exclusiveMinimum: true format: double minimum: 0 type: number high_sensitivity_crp: description: High-sensitivity C-reactive protein value example: 1.5 exclusiveMinimum: true format: double minimum: 0 type: number high_sensitivity_crp_unit: description: Unit of high-sensitivity CRP measurement enum: - mg/L - mg/dL example: mg/L type: string smoker: description: Whether the person is a smoker example: false type: boolean systolic_blood_pressure: description: Systolic blood pressure example: 120 exclusiveMinimum: true format: double minimum: 0 type: number total_cholesterol: description: Total cholesterol value example: 200 exclusiveMinimum: true format: double minimum: 0 type: number total_cholesterol_unit: description: Unit of total cholesterol measurement enum: - mg/dL - mmol/L example: mg/dL type: string required: - age - systolic_blood_pressure - total_cholesterol - total_cholesterol_unit - hdl_cholesterol - hdl_cholesterol_unit - high_sensitivity_crp - high_sensitivity_crp_unit - smoker - family_history_mi type: object ReynoldsCADRiskWomenBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/ReynoldsCADRiskWomenMetadata" description: Metadata about the calculation risk_level: description: Risk level classification example: Low type: string ten_year_risk: description: 10-year risk of cardiovascular disease (%) example: 5.2 format: double type: number required: - ten_year_risk - risk_level - metadata type: object ReynoldsCADRiskWomenMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/ReynoldsCADRiskWomenBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object SAAGBodyRequest: additionalProperties: false properties: ascites_albumin: description: Ascites albumin value example: 1.5 exclusiveMinimum: true format: double minimum: 0 type: number ascites_albumin_unit: description: Unit of ascites albumin measurement enum: - g/dL - g/L example: g/dL type: string serum_albumin: description: Serum albumin value example: 4 exclusiveMinimum: true format: double minimum: 0 type: number serum_albumin_unit: description: Unit of serum albumin measurement enum: - g/dL - g/L example: g/dL type: string required: - serum_albumin - serum_albumin_unit - ascites_albumin - ascites_albumin_unit type: object SAAGBodyResponse: additionalProperties: false properties: category: description: SAAG category (High SAAG or Low SAAG) example: High SAAG type: string metadata: $ref: "#/components/schemas/SAAGMetadata" description: Metadata about the calculation saag: description: Calculated Serum-Ascites Albumin Gradient example: 2.5 format: double type: number required: - saag - category - metadata type: object SAAGMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/SAAGBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object SIIBodyRequest: additionalProperties: false properties: lymphocyte_count: description: Lymphocyte count example: 2 exclusiveMinimum: true format: double minimum: 0 type: number lymphocyte_count_unit: description: Unit of lymphocyte count enum: - 10^9/L - 10^3/µL example: 10^9/L type: string neutrophil_count: description: Neutrophil count example: 4 exclusiveMinimum: true format: double minimum: 0 type: number neutrophil_count_unit: description: Unit of neutrophil count enum: - 10^9/L - 10^3/µL example: 10^9/L type: string platelet_count: description: Platelet count example: 200 exclusiveMinimum: true format: double minimum: 0 type: number platelet_count_unit: description: Unit of platelet count enum: - 10^9/L - 10^3/µL example: 10^9/L type: string required: - platelet_count - platelet_count_unit - neutrophil_count - neutrophil_count_unit - lymphocyte_count - lymphocyte_count_unit type: object SIIBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/SIIMetadata" description: Metadata about the calculation sii: description: Systemic Immune-Inflammation Index example: 400 format: double type: number required: - sii - metadata type: object SIIMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/SIIBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object ShockIndexBodyRequest: additionalProperties: false properties: heart_rate: description: Heart rate value (bpm) example: 80 exclusiveMinimum: true format: double minimum: 0 type: number systolic_blood_pressure: description: Systolic blood pressure value (mmHg) example: 120 exclusiveMinimum: true format: double minimum: 0 type: number required: - heart_rate - systolic_blood_pressure type: object ShockIndexBodyResponse: additionalProperties: false properties: category: description: Interpretation of the Shock Index example: Normal type: string metadata: $ref: "#/components/schemas/ShockIndexMetadata" description: Metadata about the calculation shock_index: description: Calculated Shock Index example: 0.67 format: double type: number required: - shock_index - category - metadata type: object ShockIndexMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/ShockIndexBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object SodiumCorrectionBodyRequest: additionalProperties: false properties: glucose: description: Measured glucose level example: 300 exclusiveMinimum: true format: double minimum: 0 type: number glucose_unit: description: Unit of glucose measurement enum: - mg/dL - mmol/L example: mg/dL type: string sodium: description: Measured sodium level example: 135 exclusiveMinimum: true format: double minimum: 0 type: number sodium_unit: description: Unit of measured sodium enum: - mmol/L - mEq/L example: mmol/L type: string required: - sodium - sodium_unit - glucose - glucose_unit type: object SodiumCorrectionBodyResponse: additionalProperties: false properties: corrected_sodium_hillier: description: Corrected sodium level using Hillier method (mmol/L) example: 139.8 format: double type: number corrected_sodium_katz: description: Corrected sodium level using Katz method (mmol/L) example: 138.5 format: double type: number metadata: $ref: "#/components/schemas/SodiumCorrectionMetadata" description: Metadata about the calculation required: - corrected_sodium_katz - corrected_sodium_hillier - metadata type: object SodiumCorrectionMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/SodiumCorrectionBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object TestosteroneBodyRequest: additionalProperties: false properties: albumin: description: Albumin, if not provided a default value of 4.3 g/dL will be used example: 43 format: double minimum: 0 type: number albumin_unit: description: Unit of Albumin measurement enum: - g/L - g/dL example: g/L type: string shbg: description: Sex Hormone-Binding Globulin in nmol/L example: 40 exclusiveMinimum: true format: double minimum: 0 type: number total_testosterone: description: Total Testosterone example: 15 exclusiveMinimum: true format: double minimum: 0 type: number total_testosterone_unit: description: Unit of Total Testosterone measurement enum: - nmol/L - ng/mL - ng/dL example: nmol/L type: string required: - total_testosterone - total_testosterone_unit - shbg type: object TestosteroneBodyResponse: additionalProperties: false properties: bioavailable_testosterone: $ref: "#/components/schemas/TestosteroneValues" description: Bioavailable Testosterone in various units bioavailable_testosterone_percentage: description: Bioavailable Testosterone as a percentage of Total Testosterone example: 48 format: double type: number free_testosterone: $ref: "#/components/schemas/TestosteroneValues" description: Free Testosterone in various units free_testosterone_percentage: description: Free Testosterone as a percentage of Total Testosterone example: 2 format: double type: number metadata: $ref: "#/components/schemas/TestosteroneMetadata" description: Metadata about the calculation required: - free_testosterone - bioavailable_testosterone - free_testosterone_percentage - bioavailable_testosterone_percentage - metadata type: object TestosteroneMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/TestosteroneBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object TestosteroneValues: additionalProperties: false properties: ng_dl: description: Testosterone in ng/dL example: 8.65 format: double type: number ng_ml: description: Testosterone in ng/mL example: 0.0865 format: double type: number nmol_l: description: Testosterone in nmol/L example: 0.3 format: double type: number pg_ml: description: Testosterone in pg/mL example: 300 format: double type: number pmol_l: description: Testosterone in pmol/L example: 300 format: double type: number required: - nmol_l - pmol_l - ng_dl - ng_ml - pg_ml type: object TyGBodyRequest: additionalProperties: false properties: glucose: description: Glucose value example: 100 exclusiveMinimum: true format: double minimum: 0 type: number glucose_unit: description: Unit of glucose measurement enum: - mg/dL - mmol/L example: mg/dL type: string triglycerides: description: Triglycerides value example: 150 exclusiveMinimum: true format: double minimum: 0 type: number triglycerides_unit: description: Unit of triglycerides measurement enum: - mg/dL - mmol/L example: mg/dL type: string required: - triglycerides - triglycerides_unit - glucose - glucose_unit type: object TyGBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/TyGMetadata" description: Metadata about the calculation tyg: description: Triglyceride-Glucose Index example: 8.76 format: double type: number required: - tyg - metadata type: object TyGMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/TyGBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object UIBCBodyRequest: additionalProperties: false properties: serum_iron: description: Serum Iron example: 20 format: double minimum: 0 type: number serum_iron_unit: description: Unit of Serum Iron measurement enum: - µmol/L - mmol/L - µg/dL example: µmol/L type: string tibc: description: Total Iron Binding Capacity example: 50 format: double minimum: 0 type: number tibc_unit: description: Unit of TIBC measurement enum: - µmol/L - mmol/L - µg/dL example: µmol/L type: string required: - tibc - tibc_unit - serum_iron - serum_iron_unit type: object UIBCBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/UIBCMetadata" description: Metadata about the calculation uibc: $ref: "#/components/schemas/UIBCValue" description: Calculated UIBC values required: - uibc - metadata type: object UIBCMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/UIBCBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object UIBCValue: additionalProperties: false properties: mmol_l: description: UIBC in mmol/L example: 0.03 format: double type: number µg_dl: description: UIBC in µg/dL example: 167.4 format: double type: number µmol_l: description: UIBC in µmol/L example: 30 format: double type: number required: - µmol_l - mmol_l - µg_dl type: object VAIBodyRequest: additionalProperties: false properties: bmi: description: Body Mass Index (BMI) example: 25 exclusiveMinimum: true format: double minimum: 0 type: number gender: description: Gender enum: - male - female example: female type: string hdl_cholesterol: description: HDL cholesterol value example: 50 exclusiveMinimum: true format: double minimum: 0 type: number hdl_cholesterol_unit: description: Unit of HDL cholesterol measurement enum: - mmol/L - mg/dL example: mg/dL type: string triglycerides: description: Triglycerides value example: 150 exclusiveMinimum: true format: double minimum: 0 type: number triglycerides_unit: description: Unit of triglycerides measurement enum: - mmol/L - mg/dL example: mg/dL type: string waist_circumference: description: Waist circumference example: 80 exclusiveMinimum: true format: double minimum: 0 type: number waist_circumference_unit: description: Unit of waist circumference measurement enum: - cm - in example: cm type: string required: - gender - waist_circumference - waist_circumference_unit - bmi - triglycerides - triglycerides_unit - hdl_cholesterol - hdl_cholesterol_unit type: object VAIBodyResponse: additionalProperties: false properties: metadata: $ref: "#/components/schemas/VAIMetadata" description: Metadata about the calculation vai: description: Calculated Visceral Adiposity Index example: 1.5 format: double type: number required: - vai - metadata type: object VAIMetadata: additionalProperties: false properties: calculated_at: description: Timestamp of when the calculation was performed example: "2023-06-15T14:30:00Z" type: string input: $ref: "#/components/schemas/VAIBodyRequest" description: Input measurements used in the calculation required: - calculated_at - input type: object info: description: | # Calculate Blood API This API provides access to our comprehensive suite of medical and fitness calculators. Our tools offer evidence-based estimates for various aspects of health, including: - Cardiovascular risk assessment - Liver function indices - Metabolic health markers - Hematological parameters - Renal function indicators - Body composition metrics These calculators are designed to assist healthcare professionals and researchers in making informed decisions and interpretations. However, they should not be used as a substitute for professional medical advice, diagnosis, or treatment. All calculations are based on peer-reviewed medical literature and widely accepted formulas in the field. For specific references, please refer to the documentation of each individual endpoint. Note: The results provided by these calculators are estimates and should be interpreted in the context of a patient's overall clinical picture. title: Calculate Blood API version: 1.0.0 openapi: 3.0.3 paths: /absolute-neutrophil-count: post: description: | Calculate Absolute Neutrophil Count (ANC) based on white blood cell count and neutrophil percentages. References: Newman TB, Puopolo KM, Wi S, Draper D, Escobar GJ. Interpreting complete blood counts soon after birth in newborns at risk for sepsis. Pediatrics. 2010;126(5):903-909. doi:10.1542/peds.2010-0935 requestBody: content: application/json: schema: $ref: "#/components/schemas/ANCBodyRequest" description: |- - `wbc_count` (number, required): White blood cell count. Minimum: > 0. - `wbc_count_unit` (string, required): Unit of white blood cell count measurement. Possible values: "cells/µL", "10^9/L". - `segmented_neutrophils_percent` (number, required): Percentage of segmented neutrophils. Range: 0-100. - `band_neutrophils_percent` (number, required): Percentage of band neutrophils. Range: 0-100. required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/ANCBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Absolute Neutrophil Count (ANC) tags: - Absolute Neutrophil Count (ANC) /albumin-globulin-ratio: post: description: | Calculate AGR, a marker of nutritional status and inflammation. References: Azab B, Kedia S, Shah N, et al. The value of the pretreatment albumin/globulin ratio in predicting the long-term survival in colorectal cancer. Int J Colorectal Dis. 2013;28(12):1629-1636. doi:10.1007/s00384-013-1748-z requestBody: content: application/json: schema: $ref: "#/components/schemas/AGRBodyRequest" description: |- - `albumin` (number, required): Albumin value. Minimum: > 0. - `albumin_unit` (string, required): Unit of albumin measurement. Possible values: "g/L", "g/dL". - `total_protein` (number, required): Total protein value. Minimum: > 0. - `total_protein_unit` (string, required): Unit of total protein measurement. Possible values: "g/L", "g/dL". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/AGRBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Albumin-Globulin Ratio (AGR) tags: - Albumin-Globulin Ratio (AGR) /anion-gap: post: description: | Calculate the Anion Gap to help identify acid-base disorders. The Anion Gap is the difference between the primary measured cations (sodium and optionally potassium) and the primary measured anions (chloride and bicarbonate) in serum. It is useful in the evaluation of metabolic acidosis. References: Kraut JA, Madias NE. Serum anion gap: its uses and limitations in clinical medicine. Clin J Am Soc Nephrol. 2007;2(1):162-174. doi:10.2215/CJN.03020906 Berend K, de Vries AP, Gans RO. Physiological approach to assessment of acid-base disturbances [published correction appears in N Engl J Med. 2014 Nov 13;371(20):1948]. N Engl J Med. 2014;371(15):1434-1445. doi:10.1056/NEJMra1003327 requestBody: content: application/json: schema: $ref: "#/components/schemas/AnionGapBodyRequest" description: |- - `sodium` (number, required): Sodium level. Minimum: > 0. - `sodium_unit` (string, required): Unit of sodium measurement. Possible values: "mmol/L", "mEq/L". - `potassium` (number, optional): Potassium level. Minimum: > 0. - `potassium_unit` (string, optional): Unit of potassium measurement. Possible values: "mmol/L", "mEq/L". Required if potassium is provided. - `chloride` (number, required): Chloride level. Minimum: > 0. - `chloride_unit` (string, required): Unit of chloride measurement. Possible values: "mmol/L", "mEq/L". - `bicarbonate` (number, required): Bicarbonate level. Minimum: > 0. - `bicarbonate_unit` (string, required): Unit of bicarbonate measurement. Possible values: "mmol/L", "mEq/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/AnionGapBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Anion Gap tags: - Anion Gap /apo-b-apo-a1-ratio: post: description: | Calculate the ratio of Apolipoprotein B (Apo B) to Apolipoprotein A1 (Apo A1). Useful for assessing cardiovascular risk and evaluating lipid-related disorders. Higher ratios indicate increased risk. References: Walldius G, Jungner I. The apoB/apoA-I ratio: a strong, new risk factor for cardiovascular disease and a target for lipid-lowering therapy--a review of the evidence. J Intern Med. 2006;259(5):493-519. doi:10.1111/j.1365-2796.2006.01643.x requestBody: content: application/json: schema: $ref: "#/components/schemas/ApoRatioBodyRequest" description: |- - `apo_b` (number, required): Apolipoprotein B (Apo B) value. Minimum: > 0. - `apo_b_unit` (string, required): Unit of Apo B measurement. Possible values: "g/L", "mg/dL". - `apo_a1` (number, required): Apolipoprotein A1 (Apo A1) value. Minimum: > 0. - `apo_a1_unit` (string, required): Unit of Apo A1 measurement. Possible values: "g/L", "mg/dL". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/ApoRatioBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Apo B/Apo A1 Ratio tags: - Apo B/Apo A1 Ratio /ast-to-platelet-ratio-index: post: description: | Calculate the AST to Platelet Ratio Index (APRI). Useful for assessing liver fibrosis and cirrhosis in chronic liver diseases, especially hepatitis C. References: Wai CT, Greenson JK, Fontana RJ, et al. A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology. 2003;38(2):518-526. doi:10.1053/jhep.2003.50346 requestBody: content: application/json: schema: $ref: "#/components/schemas/APRIBodyRequest" description: |- - `ast` (number, required): AST (Aspartate Aminotransferase) value. Minimum: > 0. - `ast_unit` (string, required): Unit of AST measurement. Possible values: "U/L", "µkat/L". - `platelet_count` (number, required): Platelet count value. Minimum: > 0. - `platelet_count_unit` (string, required): Unit of platelet count measurement. Possible values: "10^9/L", "10^3/µL". - `ast_upper_limit` (number, required): Laboratory upper limit of normal for AST. Minimum: > 0. - `ast_upper_limit_unit` (string, required): Unit of AST upper limit measurement. Possible values: "U/L", "µkat/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/APRIBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: AST to Platelet Ratio Index (APRI) tags: - AST to Platelet Ratio Index (APRI) /atherogenic-coefficient: post: description: | Calculate the Atherogenic Coefficient (AC), a measure of cardiovascular risk. References: Bhardwaj, S. & Bhattacharjee, Jayashree & Bhatnagar, M.K. & Tyag, S.. (2013). Atherogenic index of plasma, Castelli risk index and atherogenic coefficient- new parameters in assessing cardiovascular risk. Int. J. Pharm Bio Sci.. 3. 354-364. requestBody: content: application/json: schema: $ref: "#/components/schemas/ACBodyRequest" description: |- - `total_cholesterol` (number, required): Total cholesterol value. Minimum: > 0. - `total_cholesterol_unit` (string, required): Unit of total cholesterol measurement. Possible values: "mg/dL", "mmol/L". - `hdl_cholesterol` (number, required): HDL cholesterol value. Minimum: > 0. - `hdl_cholesterol_unit` (string, required): Unit of HDL cholesterol measurement. Possible values: "mg/dL", "mmol/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/ACBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Atherogenic Coefficient (AC) tags: - Atherogenic Coefficient (AC) /atherogenic-index-plasma: post: description: | Calculate AIP to predict cardiovascular risk based on triglycerides and HDL cholesterol levels References: Dobiásová M. AIP--aterogenní index plazmy jako významný prediktor kardiovaskulárního rizika: od výzkumu do praxe [AIP--atherogenic index of plasma as a significant predictor of cardiovascular risk: from research to practice]. Vnitr Lek. 2006;52(1):64-71. Dobiásová M, Frohlich J. The plasma parameter log (TG/HDL-C) as an atherogenic index: correlation with lipoprotein particle size and esterification rate in apoB-lipoprotein-depleted plasma (FER(HDL)). Clin Biochem. 2001;34(7):583-588. doi:10.1016/s0009-9120(01)00263-6 requestBody: content: application/json: schema: $ref: "#/components/schemas/AIPBodyRequest" description: |- - `triglycerides` (number, required): Triglycerides value. Minimum: > 0. - `triglycerides_unit` (string, required): Unit of triglycerides measurement. Possible values: "mmol/L", "mg/dL". - `hdl_cholesterol` (number, required): HDL cholesterol value. Minimum: > 0. - `hdl_cholesterol_unit` (string, required): Unit of HDL cholesterol measurement. Possible values: "mmol/L", "mg/dL". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/AIPBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Atherogenic Index of Plasma (AIP) tags: - Atherogenic Index of Plasma (AIP) /budd-chiari-syndrome-tips-prognostic-index: post: description: | Calculate the Budd-Chiari Syndrome - Transjugular Intrahepatic Portosystemic Shunt (BCS-TIPS) Prognostic Index based on age, bilirubin, and INR values. References: Garcia-Pagán JC, Heydtmann M, Raffa S, et al. TIPS for Budd-Chiari syndrome: long-term results and prognostics factors in 124 patients. Gastroenterology. 2008;135(3):808-815. doi:10.1053/j.gastro.2008.05.051 requestBody: content: application/json: schema: $ref: "#/components/schemas/BCSTIPSBodyRequest" description: |- - `age` (integer, required): Age of the person in years. Minimum: > 0. - `bilirubin` (number, required): Bilirubin value. Minimum: > 0. - `bilirubin_unit` (string, required): Unit of bilirubin measurement. Possible values: "mg/dL", "µmol/L". - `inr` (number, required): International Normalized Ratio (INR) for prothrombin time. Minimum: > 0. required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/BCSTIPSBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: BCS-TIPS Prognostic Index Calculator (BCS-TIPS) tags: - BCS-TIPS Prognostic Index Calculator (BCS-TIPS) /c-reactive-protein-albumin-ratio: post: description: | Calculate the C-Reactive Protein to Albumin Ratio (CAR). Useful for assessing inflammation and nutritional status in various conditions, particularly in predicting outcomes for cancer and critically ill patients. References: Xu HJ, Ma Y, Deng F, Ju WB, Sun XY, Wang H. The prognostic value of C-reactive protein/albumin ratio in human malignancies: an updated meta-analysis. Onco Targets Ther. 2017;10:3059-3070. Published 2017 Jun 19. doi:10.2147/OTT.S137002 requestBody: content: application/json: schema: $ref: "#/components/schemas/CRPAlbuminRatioBodyRequest" description: |- - `crp` (number, required): C-reactive protein value. Minimum: > 0. - `crp_unit` (string, required): Unit of C-reactive protein measurement. Possible values: "mg/L", "mg/dL", "nmol/L". - `albumin` (number, required): Albumin value. Minimum: > 0. - `albumin_unit` (string, required): Unit of albumin measurement. Possible values: "g/L", "g/dL". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/CRPAlbuminRatioBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: C-Reactive Protein to Albumin Ratio tags: - C-Reactive Protein to Albumin Ratio /castelli-risk-index: post: description: | Calculate Castelli Risk Index I and II to assess cardiovascular risk based on cholesterol levels. References: Castelli WP, Abbott RD, McNamara PM. Summary estimates of cholesterol used to predict coronary heart disease. Circulation. 1983;67(4):730-734. doi:10.1161/01.cir.67.4.730 Castelli WP. Cholesterol and lipids in the risk of coronary artery disease--the Framingham Heart Study. Can J Cardiol. 1988;4 Suppl A:5A-10A. requestBody: content: application/json: schema: $ref: "#/components/schemas/CastelliRiskBodyRequest" description: |- - `total_cholesterol` (number, required): Total cholesterol value. Minimum: > 0. - `total_cholesterol_unit` (string, required): Unit of total cholesterol measurement. Possible values: "mg/dL", "mmol/L". - `ldl_cholesterol` (number, required): LDL cholesterol value. Minimum: > 0. - `ldl_cholesterol_unit` (string, required): Unit of LDL cholesterol measurement. Possible values: "mg/dL", "mmol/L". - `hdl_cholesterol` (number, required): HDL cholesterol value. Minimum: > 0. - `hdl_cholesterol_unit` (string, required): Unit of HDL cholesterol measurement. Possible values: "mg/dL", "mmol/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/CastelliRiskBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Castelli Risk Index I and II tags: - Castelli Risk Index I and II /corrected-calcium: post: description: | Calculate Corrected Calcium based on total calcium and albumin levels. References: Payne RB, Little AJ, Williams RB, Milner JR. Interpretation of serum calcium in patients with abnormal serum proteins. Br Med J. 1973;4(5893):643-646. doi:10.1136/bmj.4.5893.643 requestBody: content: application/json: schema: $ref: "#/components/schemas/CorrectedCalciumBodyRequest" description: |- - `total_calcium` (number, required): Total calcium value. Minimum: > 0. - `total_calcium_unit` (string, required): Unit of total calcium measurement. Possible values: "mmol/L", "mg/dL". - `albumin` (number, required): Albumin value. Minimum: > 0. - `albumin_unit` (string, required): Unit of albumin measurement. Possible values: "g/L", "g/dL". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/CorrectedCalciumBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Corrected Calcium tags: - Corrected Calcium /creatinine-clearance: post: description: | Calculate Creatinine Clearance (CrCl) using the Cockcroft-Gault Equation for both actual and ideal body weight, calculate Ideal Body Weight (IBW) using the Devine formula. References: Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16(1):31-41. doi:10.1159/000180580 Winter MA, Guhr KN, Berg GM. Impact of various body weights and serum creatinine concentrations on the bias and accuracy of the Cockcroft-Gault equation. Pharmacotherapy. 2012;32(7):604-612. doi:10.1002/j.1875-9114.2012.01098.x requestBody: content: application/json: schema: $ref: "#/components/schemas/CrClBodyRequest" description: |- - `age` (integer, required): Age of the person in years. Minimum: > 0. - `gender` (string, required): Gender of the person. Possible values: "male", "female". - `weight` (number, required): Weight of the person. Minimum: > 0. - `weight_unit` (string, required): Unit of weight measurement. Possible values: "kg", "lb". - `height` (number, required): Height of the person. Minimum: > 0. - `height_unit` (string, required): Unit of height measurement. Possible values: "cm", "in". - `serum_creatinine` (number, required): Serum creatinine value. Minimum: > 0. - `serum_creatinine_unit` (string, required): Unit of serum creatinine measurement. Possible values: "mg/dL", "µmol/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/CrClBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Creatinine Clearance (CrCl) tags: - Creatinine Clearance (CrCl) /de-ritis-ratio: post: description: | Calculate De Ritis Ratio (AST/ALT ratio). Useful for assessing liver disease severity, differentiating causes of liver damage, and predicting outcomes in various conditions. References: Botros M, Sikaris KA. The de ritis ratio: the test of time. Clin Biochem Rev. 2013;34(3):117-130. requestBody: content: application/json: schema: $ref: "#/components/schemas/DeRitisBodyRequest" description: |- - `ast` (number, required): Aspartate Aminotransferase (AST) value. Minimum: > 0. - `ast_unit` (string, required): Unit of AST measurement. Possible values: "U/L", "µkat/L". - `alt` (number, required): Alanine Aminotransferase (ALT) value. Minimum: > 0. - `alt_unit` (string, required): Unit of ALT measurement. Possible values: "U/L", "µkat/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/DeRitisBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: De Ritis Ratio tags: - De Ritis Ratio /discriminant-function-alcoholic-hepatitis: post: description: | Calculate the modified Discriminant Function (DF) for Alcoholic Hepatitis. Helps assess the severity of alcoholic hepatitis and guides treatment decisions, particularly regarding corticosteroid therapy. References: Carithers RL Jr, Herlong HF, Diehl AM, et al. Methylprednisolone therapy in patients with severe alcoholic hepatitis. A randomized multicenter trial. Ann Intern Med. 1989;110(9):685-690. doi:10.7326/0003-4819-110-9-685 requestBody: content: application/json: schema: $ref: "#/components/schemas/DFBodyRequest" description: |- - `prothrombin_time` (number, required): Prothrombin time value in seconds. Minimum: > 0. - `control_time` (number, required): Laboratory control time for prothrombin time in seconds. Minimum: > 0. - `serum_bilirubin` (number, required): Serum bilirubin value. Minimum: > 0. - `serum_bilirubin_unit` (string, required): Unit of serum bilirubin measurement. Possible values: "mg/dL", "µmol/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/DFBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Discriminant Function (DF) for Alcoholic Hepatitis tags: - Discriminant Function (DF) for Alcoholic Hepatitis /disseminated-intravascular-coagulation-score: post: description: | Calculate the DIC Score to assess the severity of Disseminated Intravascular Coagulation (DIC). References: Levi M, Toh CH, Thachil J, Watson HG. Guidelines for the diagnosis and management of disseminated intravascular coagulation. British Committee for Standards in Haematology. Br J Haematol. 2009;145(1):24-33. doi:10.1111/j.1365-2141.2009.07600.x requestBody: content: application/json: schema: $ref: "#/components/schemas/DICBodyRequest" description: |- - `platelet_count` (number, required): Platelet count. Minimum: > 0. - `platelet_count_unit` (string, required): Unit of platelet count measurement. Possible values: "10^9/L", "10^3/µL". - `fibrin_marker` (string, required): Elevation of fibrin-related marker (e.g., D-dimer, fibrin degradation products). Possible values: "no_increase", "moderate_increase", "strong_increase". - `fibrinogen` (number, required): Fibrinogen level. Minimum: > 0. - `fibrinogen_unit` (string, required): Unit of fibrinogen measurement. Possible values: "g/L", "mg/dL". - `prothrombin_time` (number, required): Prothrombin time. Minimum: > 0. - `prothrombin_time_unit` (string, required): Unit of prothrombin time measurement. Possible values: "seconds", "INR". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/DICBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Disseminated Intravascular Coagulation (DIC) Score tags: - Disseminated Intravascular Coagulation (DIC) Score /dynamic-international-prognostic-scoring-system: post: description: | Calculate the DIPSS score for Myelofibrosis. This prognostic tool assesses risk and predicts survival in primary myelofibrosis patients. References: Passamonti F, Cervantes F, Vannucchi AM, et al. A dynamic prognostic model to predict survival in primary myelofibrosis: a study by the IWG-MRT (International Working Group for Myeloproliferative Neoplasms Research and Treatment). Blood. 2010;115(9):1703-1708. doi:10.1182/blood-2009-09-245837 requestBody: content: application/json: schema: $ref: "#/components/schemas/DIPSSBodyRequest" description: |- - `age` (integer, required): Age of the patient in years. Minimum: > 0. - `hemoglobin` (number, required): Hemoglobin level. Minimum: > 0. - `hemoglobin_unit` (string, required): Unit of hemoglobin measurement. Possible values: "g/dL", "g/L". - `wbc` (number, required): White blood cell count. Minimum: > 0. - `wbc_unit` (string, required): Unit of white blood cell count measurement. Possible values: "10^9/L", "K/µL". - `peripheral_blood_blasts` (number, required): Percentage of peripheral blood blasts. Range: 0-100. - `constitutional_symptoms` (boolean, required): Presence of constitutional symptoms (night sweats, weight loss > 10%, unexplained fever). required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/DIPSSBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Dynamic International Prognostic Scoring System (DIPSS) for Myelofibrosis tags: - Dynamic International Prognostic Scoring System (DIPSS) for Myelofibrosis /emory-model-tips: post: description: | Calculate the Emory Model (TIPS) score to predict overall mortality for patients undergoing Transjugular Intrahepatic Portosystemic Shunt (TIPS) procedure. References: Chalasani N, Clark WS, Martin LG, et al. Determinants of mortality in patients with advanced cirrhosis after transjugular intrahepatic portosystemic shunting. Gastroenterology. 2000;118(1):138-144. doi:10.1016/s0016-5085(00)70422-7 requestBody: content: application/json: schema: $ref: "#/components/schemas/EmoryModelTIPSBodyRequest" description: |- - `emergent_tips` (boolean, required): Whether the TIPS procedure is emergent. - `alt` (number, required): Alanine aminotransferase (ALT) level. Minimum: > 0. - `alt_unit` (string, required): Unit of ALT measurement. Possible values: "IU/L", "µkat/L". - `bilirubin` (number, required): Bilirubin level. Minimum: > 0. - `bilirubin_unit` (string, required): Unit of bilirubin measurement. Possible values: "mg/dL", "µmol/L". - `pre_tips_encephalopathy` (boolean, required): Whether pre-TIPS encephalopathy is present. required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/EmoryModelTIPSBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Emory Model (TIPS) Score tags: - Emory Model (TIPS) Score /estimated-average-glucose: post: description: | Calculate Estimated Average Glucose (eAG) based on HbA1c values References: Nathan DM, Kuenen J, Borg R, et al. Translating the A1C assay into estimated average glucose values [published correction appears in Diabetes Care. 2009 Jan;32(1):207]. Diabetes Care. 2008;31(8):1473-1478. doi:10.2337/dc08-0545 requestBody: content: application/json: schema: $ref: "#/components/schemas/EAGBodyRequest" description: |- - `hba1c` (number, required): HbA1c value. Minimum: > 0. - `hba1c_unit` (string, required): Unit of HbA1c measurement. Possible values: "percentage", "mmol/mol". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/EAGBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Estimated Average Glucose (eAG) tags: - Estimated Average Glucose (eAG) /estimated-glomerular-filtration-rate: post: description: | Calculate eGFR using the 2021 CKD-EPI equation (race-free) with optional Cystatin C References: Inker LA, Eneanya ND, Coresh J, et al. New Creatinine- and Cystatin C-Based Equations to Estimate GFR without Race. N Engl J Med. 2021;385(19):1737-1749. doi:10.1056/NEJMoa2102953 requestBody: content: application/json: schema: $ref: "#/components/schemas/EGFRBodyRequest" description: |- - `age` (integer, required): Age of the person in years. Range: 18-150. - `gender` (string, required): Gender of the person. Possible values: "male", "female". - `serum_creatinine` (number, required): Serum creatinine value. Minimum: > 0. - `serum_creatinine_unit` (string, required): Unit of serum creatinine measurement. Possible values: "mg/dL", "µmol/L". - `serum_cystatin_c` (number, optional): Serum cystatin C value in mg/L. Minimum: > 0. required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/EGFRBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Estimated Glomerular Filtration Rate (eGFR) tags: - Estimated Glomerular Filtration Rate (eGFR) /fatty-liver-index: post: description: | Calculate the Fatty Liver Index (FLI) to predict the presence of fatty liver. References: Bedogni G, Bellentani S, Miglioli L, et al. The Fatty Liver Index: a simple and accurate predictor of hepatic steatosis in the general population. BMC Gastroenterol. 2006;6:33. Published 2006 Nov 2. doi:10.1186/1471-230X-6-33 requestBody: content: application/json: schema: $ref: "#/components/schemas/FLIBodyRequest" description: |- - `bmi` (number, required): Body Mass Index (BMI). Minimum: > 0. - `waist_circumference` (number, required): Waist circumference. Minimum: > 0. - `waist_circumference_unit` (string, required): Unit of waist circumference measurement. Possible values: "cm", "in". - `triglycerides` (number, required): Triglycerides value. Minimum: > 0. - `triglycerides_unit` (string, required): Unit of triglycerides measurement. Possible values: "mg/dL", "mmol/L". - `ggt` (number, required): Gamma-glutamyl transferase (GGT) value. Minimum: > 0. - `ggt_unit` (string, required): Unit of GGT measurement. Possible values: "U/L", "µkat/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/FLIBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Fatty Liver Index (FLI) tags: - Fatty Liver Index (FLI) /fibrinogen-to-albumin-ratio: post: description: | Calculate the Fibrinogen-to-Albumin Ratio (FAR), a prognostic marker in cancer patients. References: Tan Z, Zhang M, Han Q, et al. A novel blood tool of cancer prognosis in esophageal squamous cell carcinoma: the Fibrinogen/Albumin Ratio. J Cancer. 2017;8(6):1025-1029. Published 2017 Apr 8. doi:10.7150/jca.16491 requestBody: content: application/json: schema: $ref: "#/components/schemas/FARBodyRequest" description: |- - `fibrinogen` (number, required): Fibrinogen value. Minimum: > 0. - `fibrinogen_unit` (string, required): Unit of fibrinogen measurement. Possible values: "g/L", "mg/dL". - `albumin` (number, required): Albumin value. Minimum: > 0. - `albumin_unit` (string, required): Unit of albumin measurement. Possible values: "g/L", "g/dL". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/FARBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Fibrinogen-to-Albumin Ratio (FAR) tags: - Fibrinogen-to-Albumin Ratio (FAR) /fibrosis-4-index: post: description: | Calculate the Fibrosis-4 (FIB-4) Index to estimate the amount of scarring in the liver. References: Sterling RK, Lissen E, Clumeck N, et al. Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection. Hepatology. 2006;43(6):1317-1325. doi:10.1002/hep.21178 requestBody: content: application/json: schema: $ref: "#/components/schemas/FIB4BodyRequest" description: |- - `age` (integer, required): Age of the person in years. Minimum: > 0. - `ast` (number, required): Aspartate aminotransferase (AST) value. Minimum: > 0. - `ast_unit` (string, required): Unit of AST measurement. Possible values: "U/L", "µkat/L". - `alt` (number, required): Alanine aminotransferase (ALT) value. Minimum: > 0. - `alt_unit` (string, required): Unit of ALT measurement. Possible values: "U/L", "µkat/L". - `platelet_count` (number, required): Platelet count. Minimum: > 0. - `platelet_count_unit` (string, required): Unit of platelet count measurement. Possible values: "10^9/L", "10^3/µL". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/FIB4BodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Fibrosis-4 (FIB-4) Index tags: - Fibrosis-4 (FIB-4) Index /follicular-lymphoma-international-prognostic-index: post: description: | Calculate the Follicular Lymphoma International Prognostic Index (FLIPI) score. References: Solal-Céligny P, Roy P, Colombat P, et al. Follicular lymphoma international prognostic index. Blood. 2004;104(5):1258-1265. doi:10.1182/blood-2003-12-4434 requestBody: content: application/json: schema: $ref: "#/components/schemas/FLIPIBodyRequest" description: |- - `age` (integer, required): Age of the patient in years. Minimum: > 0. - `ann_arbor_stage` (integer, required): Ann Arbor stage. Possible values: 1, 2, 3, 4. - `hemoglobin` (number, required): Hemoglobin level. Minimum: > 0. - `hemoglobin_unit` (string, required): Unit of hemoglobin measurement. Possible values: "g/dL", "g/L". - `ldh` (number, required): Lactate dehydrogenase (LDH) level. Minimum: > 0. - `ldh_unit` (string, required): Unit of LDH measurement. Possible values: "U/L", "µkat/L". - `ldh_upper_limit` (number, required): Laboratory upper limit of normal for LDH. Minimum: > 0. - `ldh_upper_limit_unit` (string, required): Unit of LDH upper limit measurement. Possible values: "U/L", "µkat/L". - `nodal_sites` (integer, required): Number of nodal sites. Minimum: >= 0. required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/FLIPIBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Follicular Lymphoma International Prognostic Index (FLIPI) tags: - Follicular Lymphoma International Prognostic Index (FLIPI) /fractional-excretion-of-sodium: post: description: | Calculate Fractional Excretion of Sodium (FENa) to assess the cause of acute kidney injury References: Espinel CH. The FENa test. Use in the differential diagnosis of acute renal failure. JAMA. 1976;236(6):579-581. doi:10.1001/jama.236.6.579 requestBody: content: application/json: schema: $ref: "#/components/schemas/FENaBodyRequest" description: |- - `serum_sodium` (number, required): Serum sodium value. Minimum: > 0. - `serum_sodium_unit` (string, required): Unit of serum sodium measurement. Possible values: "mmol/L", "mEq/L". - `urine_sodium` (number, required): Urine sodium value. Minimum: > 0. - `urine_sodium_unit` (string, required): Unit of urine sodium measurement. Possible values: "mmol/L", "mEq/L". - `serum_creatinine` (number, required): Serum creatinine value. Minimum: > 0. - `serum_creatinine_unit` (string, required): Unit of serum creatinine measurement. Possible values: "mg/dL", "µmol/L". - `urine_creatinine` (number, required): Urine creatinine value. Minimum: > 0. - `urine_creatinine_unit` (string, required): Unit of urine creatinine measurement. Possible values: "mg/dL", "µmol/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/FENaBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Fractional Excretion of Sodium (FENa) tags: - Fractional Excretion of Sodium (FENa) /framingham-cvd-risk-score: post: description: | Calculate the Framingham CVD Risk Score to estimate 10-year cardiovascular disease (CVD) risk References: D'Agostino RB Sr, Vasan RS, Pencina MJ, Wolf PA, Cobain M, Massaro JM, Kannel WB. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation. 2008;117(6):743-753. doi:10.1161/CIRCULATIONAHA.107.699579 requestBody: content: application/json: schema: $ref: "#/components/schemas/FraminghamCVDBodyRequest" description: |- - `age` (integer, required): Age in years. Range: 30-74. - `gender` (string, required): Gender of the person. Possible values: "male", "female". - `total_cholesterol` (number, required): Total cholesterol value. Minimum: > 0. - `total_cholesterol_unit` (string, required): Unit of total cholesterol measurement. Possible values: "mg/dL", "mmol/L". - `hdl_cholesterol` (number, required): HDL cholesterol value. Minimum: > 0. - `hdl_cholesterol_unit` (string, required): Unit of HDL cholesterol measurement. Possible values: "mg/dL", "mmol/L". - `systolic_blood_pressure` (number, required): Systolic blood pressure value. Minimum: > 0. - `is_on_blood_pressure_medication` (boolean, required): Whether the person is on blood pressure medication. - `is_smoker` (boolean, required): Whether the person is a smoker. - `diabetes` (boolean, required): Whether the person has diabetes. required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/FraminghamCVDBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Framingham CVD Risk Score tags: - Framingham CVD Risk Score /free-testosterone: post: description: | Calculate Free and Bioavailable Testosterone using the Vermeulen model (JCEM 1999;84:3666-3672) References: Vermeulen A, Verdonck L, Kaufman JM. A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab. 1999;84(10):3666-3672. doi:10.1210/jcem.84.10.6079 requestBody: content: application/json: schema: $ref: "#/components/schemas/TestosteroneBodyRequest" description: |- - `total_testosterone` (number, required): Total Testosterone value. Minimum: > 0. - `total_testosterone_unit` (string, required): Unit of Total Testosterone measurement. Possible values: "nmol/L", "ng/mL", "ng/dL". - `shbg` (number, required): Sex Hormone-Binding Globulin in nmol/L. Minimum: > 0. - `albumin` (number, optional): Albumin value. Minimum: >= 0. If not provided, a default value of 4.3 g/dL will be used. - `albumin_unit` (string, optional): Unit of Albumin measurement. Possible values: "g/L", "g/dL". Required if albumin is provided. required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/TestosteroneBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Free and Bioavailable Testosterone tags: - Free and Bioavailable Testosterone /free-water-clearance: post: description: | Calculate Free Water Clearance to assess the kidney's ability to excrete free water. References: Rose, B.D. and Post, T.W., (2001) Clinical physiology of acid-base and electrolyte disorders. 5th Edition, McGraw-Hill, New York. requestBody: content: application/json: schema: $ref: "#/components/schemas/FWCBodyRequest" description: |- - `urine_flow_rate` (number, required): Urine flow rate. Minimum: > 0. - `urine_flow_rate_unit` (string, required): Unit of urine flow rate measurement. Possible values: "mL/min", "L/day". - `urine_osmolality` (number, required): Urine osmolality. Minimum: > 0. - `urine_osmolality_unit` (string, required): Unit of urine osmolality measurement. Possible values: "mOsm/kg", "mmol/kg". - `plasma_osmolality` (number, required): Plasma osmolality. Minimum: > 0. - `plasma_osmolality_unit` (string, required): Unit of plasma osmolality measurement. Possible values: "mOsm/kg", "mmol/kg". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/FWCBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Free Water Clearance tags: - Free Water Clearance /galad-model: post: description: | Calculate the GALAD score for Hepatocellular Carcinoma (HCC) detection based on Gender, Age, AFP-L3, AFP, and DCP. References: Johnson PJ, Pirrie SJ, Cox TF, et al. The detection of hepatocellular carcinoma using a prospectively developed and validated model based on serological biomarkers. Cancer Epidemiol Biomarkers Prev. 2014;23(1):144-153. doi:10.1158/1055-9965.EPI-13-0870 requestBody: content: application/json: schema: $ref: "#/components/schemas/GALADBodyRequest" description: |- - `gender` (string, required): Gender of the person. Possible values: "male", "female". - `age` (number, required): Age of the person in years. Minimum: > 0. - `afp` (number, required): AFP value. Minimum: > 0. - `afp_unit` (string, required): Unit of AFP measurement. Possible values: "ng/mL", "IU/mL", "kIU/L". - `afp_l3_percent` (number, required): AFP-L3 value in percent. Minimum: >= 0. - `dcp` (number, required): DCP value. Minimum: > 0. - `dcp_unit` (string, required): Unit of DCP measurement. Possible values: "ng/mL", "mAU/mL". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/GALADBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: GALAD Model for Hepatocellular Carcinoma (HCC) tags: - GALAD Model for Hepatocellular Carcinoma (HCC) /gamma-glutamyl-transferase-to-platelet-ratio: post: description: | Calculate GPR, a non-invasive marker of liver fibrosis. Formula: GPR = (GGT / Upper Limit of Normal GGT) / Platelet Count * 100 References: Lemoine M, Shimakawa Y, Nayagam S, et al. The gamma-glutamyl transpeptidase to platelet ratio (GPR) predicts significant liver fibrosis and cirrhosis in patients with chronic HBV infection in West Africa. Gut. 2016;65(8):1369-1376. doi:10.1136/gutjnl-2015-309260 requestBody: content: application/json: schema: $ref: "#/components/schemas/GPRBodyRequest" description: |- - `ggt` (number, required): Gamma-Glutamyl Transferase (GGT) value. Minimum: > 0. - `ggt_unit` (string, required): Unit of GGT measurement. Possible values: "U/L", "µkat/L". - `uln_ggt` (number, required): Upper Limit of Normal GGT value. Minimum: > 0. - `uln_ggt_unit` (string, required): Unit of Upper Limit of Normal GGT measurement. Possible values: "U/L", "µkat/L". - `platelet_count` (number, required): Platelet Count value. Minimum: > 0. - `platelet_count_unit` (string, required): Unit of Platelet Count measurement. Possible values: "10^9/L", "10^3/µL". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/GPRBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Gamma-Glutamyl Transferase to Platelet Ratio (GPR) tags: - Gamma-Glutamyl Transferase to Platelet Ratio (GPR) /ganzoni-equation: post: description: | Calculate the total iron deficit using the Ganzoni Equation for Iron Deficiency Anemia. References: Ganzoni AM. Eisen-Dextran intravenös: therapeutische und experimentelle Möglichkeiten [Intravenous iron-dextran: therapeutic and experimental possibilities]. Schweiz Med Wochenschr. 1970;100(7):301-303. requestBody: content: application/json: schema: $ref: "#/components/schemas/GanzoniBodyRequest" description: |- - `weight` (number, required): Body weight. Minimum: > 0. - `weight_unit` (string, required): Unit of body weight. Possible values: "kg", "lb". - `hemoglobin` (number, required): Current hemoglobin level. Minimum: > 0. - `hemoglobin_unit` (string, required): Unit of hemoglobin measurement. Possible values: "g/dL", "g/L". - `target_hemoglobin` (number, required): Target hemoglobin level. Minimum: > 0. - `target_hemoglobin_unit` (string, required): Unit of target hemoglobin measurement. Possible values: "g/dL", "g/L". - `storage_iron` (number, optional): Storage iron. Default: 500 mg. Minimum: >= 0. required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/GanzoniBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Ganzoni Equation for Iron Deficiency Anemia tags: - Ganzoni Equation for Iron Deficiency Anemia /homeostatic-model-assessment-insulin-resistance: post: description: | Calculate HOMA-IR to estimate insulin resistance References: Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412-419. doi:10.1007/BF00280883 requestBody: content: application/json: schema: $ref: "#/components/schemas/HOMAIRBodyRequest" description: |- - `fasting_glucose` (number, required): Fasting glucose value. Minimum: > 0. - `fasting_glucose_unit` (string, required): Unit of fasting glucose measurement. Possible values: "mg/dL", "mmol/L", "mIU/L". - `fasting_insulin` (number, required): Fasting insulin value. Minimum: > 0. - `fasting_insulin_unit` (string, required): Unit of fasting insulin measurement. Possible values: "µIU/mL", "pmol/L", "mIU/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/HOMAIRBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) tags: - Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) /international-prognostic-scoring-system-waldenstrom-macroglobulinemia: post: description: | Calculate the International Prognostic Scoring System for Waldenström Macroglobulinemia (IPSSWM) References: Morel P, Duhamel A, Gobbi P, et al. International prognostic scoring system for Waldenstrom macroglobulinemia. Blood. 2009;113(18):4163-4170. doi:10.1182/blood-2008-08-174961 requestBody: content: application/json: schema: $ref: "#/components/schemas/IPSSWMBodyRequest" description: |- - `age` (integer, required): Age of the patient in years. Minimum: > 0. - `hemoglobin` (number, required): Hemoglobin value. Minimum: > 0. - `hemoglobin_unit` (string, required): Unit of hemoglobin measurement. Possible values: "g/dL", "g/L". - `platelet_count` (number, required): Platelet count. Minimum: > 0. - `platelet_count_unit` (string, required): Unit of platelet count. Possible values: "10^9/L", "10^3/µL". - `beta2_microglobulin` (number, required): Beta-2 microglobulin value. Minimum: > 0. - `beta2_microglobulin_unit` (string, required): Unit of beta-2 microglobulin measurement. Possible values: "mg/L", "µg/L", "µg/mL". - `monoclonal_igm` (number, required): Monoclonal IgM value. Minimum: > 0. - `monoclonal_igm_unit` (string, required): Unit of monoclonal IgM measurement. Possible values: "g/L", "g/dL". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/IPSSWMBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: International Prognostic Scoring System for Waldenström Macroglobulinemia (IPSSWM) tags: - International Prognostic Scoring System for Waldenström Macroglobulinemia (IPSSWM) /ldl-calculator: post: description: | Calculate LDL cholesterol using the Friedewald equation based on total cholesterol, HDL cholesterol, and triglycerides. References: Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines [published correction appears in Circulation. 2019 Jun 18;139(25):e1182-e1186. doi: 10.1161/CIR.0000000000000698] [published correction appears in Circulation. 2023 Aug 15;148(7):e5. doi: 10.1161/CIR.0000000000001172]. Circulation. 2019;139(25):e1082-e1143. doi:10.1161/CIR.0000000000000625 requestBody: content: application/json: schema: $ref: "#/components/schemas/LDLCalculatorBodyRequest" description: |- - `total_cholesterol` (number, required): Total cholesterol value. Minimum: > 0. - `total_cholesterol_unit` (string, required): Unit of total cholesterol measurement. Possible values: "mg/dL", "mmol/L". - `hdl_cholesterol` (number, required): HDL cholesterol value. Minimum: > 0. - `hdl_cholesterol_unit` (string, required): Unit of HDL cholesterol measurement. Possible values: "mg/dL", "mmol/L". - `triglycerides` (number, required): Triglycerides value. Minimum: > 0. - `triglycerides_unit` (string, required): Unit of triglycerides measurement. Possible values: "mg/dL", "mmol/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/LDLCalculatorBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: LDL Cholesterol tags: - LDL Cholesterol /lipid-accumulation-product: post: description: | Calculate Lipid Accumulation Product (LAP), a marker of central lipid accumulation. References: Kahn HS. The "lipid accumulation product" performs better than the body mass index for recognizing cardiovascular risk: a population-based comparison [published correction appears in BMC Cardiovasc Disord. 2006;6:5]. BMC Cardiovasc Disord. 2005;5:26. Published 2005 Sep 8. doi:10.1186/1471-2261-5-26 requestBody: content: application/json: schema: $ref: "#/components/schemas/LAPBodyRequest" description: |- - `gender` (string, required): Gender of the person. Possible values: "male", "female". - `waist_circumference` (number, required): Waist circumference. Minimum: > 0. - `waist_circumference_unit` (string, required): Unit of waist circumference measurement. Possible values: "cm", "in". - `triglycerides` (number, required): Triglycerides value. Minimum: > 0. - `triglycerides_unit` (string, required): Unit of triglycerides measurement. Possible values: "mg/dL", "mmol/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/LAPBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Lipid Accumulation Product (LAP) tags: - Lipid Accumulation Product (LAP) /lymphocyte-monocyte-ratio: post: description: | Calculate the Lymphocyte-to-Monocyte Ratio (LMR), a marker of systemic inflammation. References: Gong S, Gao X, Xu F, et al. Association of lymphocyte to monocyte ratio with severity of coronary artery disease. Medicine (Baltimore). 2018;97(43):e12813. doi:10.1097/MD.0000000000012813 requestBody: content: application/json: schema: $ref: "#/components/schemas/LMRBodyRequest" description: |- - `lymphocyte_count` (number, required): Lymphocyte count. Minimum: > 0. - `lymphocyte_count_unit` (string, required): Unit of lymphocyte count. Possible values: "10^9/L", "cells/µL". - `monocyte_count` (number, required): Monocyte count. Minimum: > 0. - `monocyte_count_unit` (string, required): Unit of monocyte count. Possible values: "10^9/L", "cells/µL". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/LMRBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Lymphocyte-to-Monocyte Ratio (LMR) tags: - Lymphocyte-to-Monocyte Ratio (LMR) /metabolic-syndrome: post: description: | Calculate Metabolic Syndrome (MetS) based on the NCEP ATP III criteria. References: National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation. 2002;106(25):3143-3421. requestBody: content: application/json: schema: $ref: "#/components/schemas/MetSBodyRequest" description: |- - `gender` (string, required): Gender of the person. Possible values: "male", "female". - `waist_circumference` (number, required): Waist circumference. Minimum: > 0. - `waist_circumference_unit` (string, required): Unit of waist circumference measurement. Possible values: "cm", "in". - `triglycerides` (number, required): Triglycerides level. Minimum: > 0. - `triglycerides_unit` (string, required): Unit of triglycerides measurement. Possible values: "mg/dL", "mmol/L". - `hdl_cholesterol` (number, required): HDL cholesterol level. Minimum: > 0. - `hdl_cholesterol_unit` (string, required): Unit of HDL cholesterol measurement. Possible values: "mg/dL", "mmol/L". - `blood_pressure_systolic` (number, required): Systolic blood pressure. Minimum: > 0. - `blood_pressure_diastolic` (number, required): Diastolic blood pressure. Minimum: > 0. - `fasting_glucose` (number, required): Fasting glucose level. Minimum: > 0. - `fasting_glucose_unit` (string, required): Unit of fasting glucose measurement. Possible values: "mg/dL", "mmol/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/MetSBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Metabolic Syndrome (MetS) tags: - Metabolic Syndrome (MetS) /modified-glasgow-prognostic-score: post: description: | Calculate the Modified Glasgow Prognostic Score (mGPS), an inflammation-based prognostic score. References: Proctor MJ, Morrison DS, Talwar D, et al. An inflammation-based prognostic score (mGPS) predicts cancer survival independent of tumour site: a Glasgow Inflammation Outcome Study. Br J Cancer. 2011;104(4):726-734. doi:10.1038/sj.bjc.6606087 requestBody: content: application/json: schema: $ref: "#/components/schemas/MGPSBodyRequest" description: |- - `c_reactive_protein` (number, required): C-reactive protein (CRP) value. Minimum: > 0. - `c_reactive_protein_unit` (string, required): Unit of CRP measurement. Possible values: "mg/L", "mg/dL". - `albumin` (number, required): Albumin value. Minimum: > 0. - `albumin_unit` (string, required): Unit of albumin measurement. Possible values: "g/L", "g/dL". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/MGPSBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Modified Glasgow Prognostic Score (mGPS) tags: - Modified Glasgow Prognostic Score (mGPS) /modified-henderson-equation: post: description: | Calculate hydrogen ion concentration [H+] and pH using the modified Henderson equation: [H+] = 24 x PCO2 / HCO3- References: Sood P, Paul G, Puri S. Interpretation of arterial blood gas. Indian J Crit Care Med. 2010;14(2):57-64. doi:10.4103/0972-5229.68215 requestBody: content: application/json: schema: $ref: "#/components/schemas/ModifiedHendersonBodyRequest" description: |- - `pco2` (number, required): Partial pressure of carbon dioxide (PCO2). Minimum: > 0. - `pco2_unit` (string, required): Unit of PCO2 measurement. Possible values: "mmHg", "kPa". - `hco3` (number, required): Bicarbonate (HCO3-) concentration. Minimum: > 0. - `hco3_unit` (string, required): Unit of HCO3- measurement. Possible values: "mEq/L", "mmol/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/ModifiedHendersonBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Modified Henderson Equation tags: - Modified Henderson Equation /monocyte-hdl-ratio: post: description: | Calculate MHR, a marker of inflammation and oxidative stress References: Canpolat U, Çetin EH, Cetin S, et al. Association of Monocyte-to-HDL Cholesterol Ratio with Slow Coronary Flow is Linked to Systemic Inflammation. Clin Appl Thromb Hemost. 2016;22(5):476-482. doi:10.1177/1076029615594002 requestBody: content: application/json: schema: $ref: "#/components/schemas/MHRBodyRequest" description: |- - `monocyte_count` (number, required): Monocyte count value. Minimum: > 0. - `monocyte_count_unit` (string, required): Unit of monocyte count measurement. Possible values: "10^9/L", "cells/µL". - `hdl_cholesterol` (number, required): HDL cholesterol value. Minimum: > 0. - `hdl_cholesterol_unit` (string, required): Unit of HDL cholesterol measurement. Possible values: "mmol/L", "mg/dL". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/MHRBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Monocyte-to-HDL Ratio (MHR) tags: - Monocyte-to-HDL Ratio (MHR) /multiple-myeloma-prognosis: post: description: | Calculate Multiple Myeloma Prognosis using the International Staging System (ISS) References: Greipp PR, San Miguel J, Durie BG, et al. International staging system for multiple myeloma [published correction appears in J Clin Oncol. 2005 Sep 1;23(25):6281. Harousseau, Jean-Luc [corrected to Avet-Loiseau, Herve]]. J Clin Oncol. 2005;23(15):3412-3420. doi:10.1200/JCO.2005.04.242 requestBody: content: application/json: schema: $ref: "#/components/schemas/MMPBodyRequest" description: |- - `beta2_microglobulin` (number, required): Serum β2-microglobulin value. Minimum: > 0. - `beta2_microglobulin_unit` (string, required): Unit of serum β2-microglobulin measurement. Possible values: "mg/L", "µg/L", "µg/mL". - `albumin` (number, required): Serum albumin value. Minimum: > 0. - `albumin_unit` (string, required): Unit of serum albumin measurement. Possible values: "g/dL", "g/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/MMPBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Multiple Myeloma Prognosis (ISS) tags: - Multiple Myeloma Prognosis (ISS) /nafld-fibrosis-score: post: description: | Calculate the NAFLD (Non-Alcoholic Fatty Liver Disease) Fibrosis Score to estimate the amount of scarring in the liver based on several laboratory tests. References: Angulo P, Hui JM, Marchesini G, et al. The NAFLD fibrosis score: a noninvasive system that identifies liver fibrosis in patients with NAFLD. Hepatology. 2007;45(4):846-854. doi:10.1002/hep.21496 requestBody: content: application/json: schema: $ref: "#/components/schemas/NAFLDBodyRequest" description: |- - `age` (integer, required): Age of the person in years. Minimum: > 0. - `bmi` (number, required): Body Mass Index (BMI). Minimum: > 0. - `diabetes` (boolean, required): Presence of diabetes or impaired fasting glucose. - `ast` (number, required): Aspartate Aminotransferase (AST) value. Minimum: > 0. - `ast_unit` (string, required): Unit of AST measurement. Possible values: "U/L", "µkat/L". - `alt` (number, required): Alanine Aminotransferase (ALT) value. Minimum: > 0. - `alt_unit` (string, required): Unit of ALT measurement. Possible values: "U/L", "µkat/L". - `platelets` (number, required): Platelet count. Minimum: > 0. - `platelets_unit` (string, required): Unit of platelet count measurement. Possible values: "10^9/L", "10^3/µL". - `albumin` (number, required): Albumin value. Minimum: > 0. - `albumin_unit` (string, required): Unit of albumin measurement. Possible values: "g/dL", "g/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/NAFLDBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: NAFLD Fibrosis Score tags: - NAFLD Fibrosis Score /neutrophil-to-albumin-ratio: post: description: | Calculate Neutrophil-to-Albumin Ratio (NAR), a prognostic marker in various diseases. References: Hu Z, Wang J, Xue Y, et al. The Neutrophil-to-Albumin Ratio as a New Predictor of All-Cause Mortality in Patients with Heart Failure. J Inflamm Res. 2022;15:701-713. Published 2022 Feb 2. doi:10.2147/JIR.S349996 requestBody: content: application/json: schema: $ref: "#/components/schemas/NARBodyRequest" description: |- - `neutrophil_count` (number, required): Neutrophil count value. Minimum: > 0. - `neutrophil_count_unit` (string, required): Unit of neutrophil count measurement. Possible values: "10^9/L", "cells/µL". - `albumin` (number, required): Albumin value. Minimum: > 0. - `albumin_unit` (string, required): Unit of albumin measurement. Possible values: "g/dL", "g/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/NARBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Neutrophil-to-Albumin Ratio (NAR) tags: - Neutrophil-to-Albumin Ratio (NAR) /osmolal-gap: post: description: | Calculate Osmolal Gap based on measured osmolality and individual components. Osmolal Gap = Measured Osmolality - Calculated Osmolality Calculated Serum Osmolality = 1.86(Na + K) + 1.15(Glu / 18) + (Urea / 6) + 14 References: Martín-Calderón JL, Bustos F, Tuesta-Reina LR, Varona JM, Caballero L, Solano F. Choice of the best equation for plasma osmolality calculation: Comparison of fourteen formulae. Clin Biochem. 2015;48(7-8):529-533. doi:10.1016/j.clinbiochem.2015.03.005 requestBody: content: application/json: schema: $ref: "#/components/schemas/OsmolalGapBodyRequest" description: |- - `measured_osmolality` (number, required): Measured osmolality value. Minimum: > 0. - `measured_osmolality_unit` (string, required): Unit of measured osmolality. Possible values: "mOsm/kg", "mmol/kg". - `sodium` (number, required): Sodium (Na) concentration. Minimum: > 0. - `sodium_unit` (string, required): Unit of sodium concentration. Possible values: "mEq/L", "mmol/L". - `potassium` (number, required): Potassium (K) concentration. Minimum: > 0. - `potassium_unit` (string, required): Unit of potassium concentration. Possible values: "mEq/L", "mmol/L". - `glucose` (number, required): Glucose concentration. Minimum: > 0. - `glucose_unit` (string, required): Unit of glucose concentration. Possible values: "mg/dL", "mmol/L". - `urea` (number, required): Urea concentration. Minimum: > 0. - `urea_unit` (string, required): Unit of urea concentration. Possible values: "mg/dL", "mmol/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/OsmolalGapBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Osmolal Gap tags: - Osmolal Gap /oxygen-content: post: description: | Calculate Oxygen Content (CaO2) in arterial blood References: Zander R, Mertzlufft F. Oxygen parameters of blood: definitions and symbols. Scand J Clin Lab Invest Suppl. 1990;203:177-185. doi:10.3109/00365519009087508 requestBody: content: application/json: schema: $ref: "#/components/schemas/CaO2BodyRequest" description: |- - `hemoglobin` (number, required): Hemoglobin concentration. Minimum: > 0. - `hemoglobin_unit` (string, required): Unit of hemoglobin measurement. Possible values: "g/dL", "g/L". - `oxygen_saturation` (number, required): Oxygen saturation (SaO2) in %. Minimum: 0, Maximum: 100. - `partial_pressure_oxygen` (number, required): Partial pressure of oxygen (PaO2). Minimum: > 0. - `partial_pressure_oxygen_unit` (string, required): Unit of PaO2 measurement. Possible values: "mmHg", "kPa". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/CaO2BodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Oxygen Content (CaO2) tags: - Oxygen Content (CaO2) /prognostic-nutritional-index: post: description: | Calculate Prognostic Nutritional Index (PNI) to assess nutritional and immunological status References: Ellez HI, Keskinkilic M, Semiz HS, Arayici ME, Kısa E, Oztop I. The Prognostic Nutritional Index (PNI): A New Biomarker for Determining Prognosis in Metastatic Castration-Sensitive Prostate Carcinoma. J Clin Med. 2023;12(17):5434. Published 2023 Aug 22. doi:10.3390/jcm12175434 requestBody: content: application/json: schema: $ref: "#/components/schemas/PNIBodyRequest" description: |- - `serum_albumin` (number, required): Serum albumin value. Minimum: > 0. - `serum_albumin_unit` (string, required): Unit of serum albumin measurement. Possible values: "g/dL", "g/L". - `total_lymphocyte_count` (number, required): Total lymphocyte count. Minimum: > 0. - `total_lymphocyte_count_unit` (string, required): Unit of total lymphocyte count measurement. Possible values: "cells/µL", "cells/mm^3", "10^9/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/PNIBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Prognostic Nutritional Index (PNI) tags: - Prognostic Nutritional Index (PNI) /quantitative-insulin-sensitivity-check-index: post: description: | Calculate QUICKI to assess insulin sensitivity References: Katz A, Nambi SS, Mather K, et al. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab. 2000;85(7):2402-2410. doi:10.1210/jcem.85.7.6661 requestBody: content: application/json: schema: $ref: "#/components/schemas/QUICKIBodyRequest" description: |- - `fasting_glucose` (number, required): Fasting glucose value. Minimum: > 0. - `fasting_glucose_unit` (string, required): Unit of fasting glucose measurement. Possible values: "mg/dL", "mmol/L", "mIU/L". - `fasting_insulin` (number, required): Fasting insulin value. Minimum: > 0. - `fasting_insulin_unit` (string, required): Unit of fasting insulin measurement. Possible values: "µIU/mL", "pmol/L", "mIU/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/QUICKIBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Quantitative Insulin Sensitivity Check Index (QUICKI) tags: - Quantitative Insulin Sensitivity Check Index (QUICKI) /red-cell-distribution-width-to-platelet-ratio: post: description: | Calculate RPR, a predictor of fibrosis in liver diseases References: Chen B, Ye B, Zhang J, Ying L, Chen Y. RDW to platelet ratio: a novel noninvasive index for predicting hepatic fibrosis and cirrhosis in chronic hepatitis B. PLoS One. 2013;8(7):e68780. Published 2013 Jul 17. doi:10.1371/journal.pone.0068780 requestBody: content: application/json: schema: $ref: "#/components/schemas/RPRBodyRequest" description: |- - `rdw` (number, required): Red Cell Distribution Width value in %. Minimum: > 0. - `platelet_count` (number, required): Platelet Count value. Minimum: > 0. - `platelet_count_unit` (string, required): Unit of Platelet Count measurement. Possible values: "10^9/L", "10^3/µL". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/RPRBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Red Cell Distribution Width to Platelet Ratio (RPR) tags: - Red Cell Distribution Width to Platelet Ratio (RPR) /remnant-cholesterol: post: description: | Calculate remnant cholesterol based on total cholesterol, HDL cholesterol, and LDL cholesterol. References: Varbo A, Benn M, Tybjærg-Hansen A, Jørgensen AB, Frikke-Schmidt R, Nordestgaard BG. Remnant cholesterol as a causal risk factor for ischemic heart disease [published correction appears in J Am Coll Cardiol. 2019 Mar 5;73(8):987-988. doi: 10.1016/j.jacc.2019.01.006]. J Am Coll Cardiol. 2013;61(4):427-436. doi:10.1016/j.jacc.2012.08.1026 requestBody: content: application/json: schema: $ref: "#/components/schemas/RemnantCholesterolBodyRequest" description: |- - `total_cholesterol` (number, required): Total cholesterol value. Minimum: > 0. - `total_cholesterol_unit` (string, required): Unit of total cholesterol measurement. Possible values: "mg/dL", "mmol/L". - `hdl_cholesterol` (number, required): HDL cholesterol value. Minimum: > 0. - `hdl_cholesterol_unit` (string, required): Unit of HDL cholesterol measurement. Possible values: "mg/dL", "mmol/L". - `ldl_cholesterol` (number, required): LDL cholesterol value. Minimum: > 0. - `ldl_cholesterol_unit` (string, required): Unit of LDL cholesterol measurement. Possible values: "mg/dL", "mmol/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/RemnantCholesterolBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Remnant Cholesterol tags: - Remnant Cholesterol /reticulocyte-production-index: post: description: | Calculate the Reticulocyte Production Index (RPI) to assess bone marrow response to anemia References: Piva E, Brugnara C, Spolaore F, Plebani M. Clinical utility of reticulocyte parameters. Clin Lab Med. 2015;35(1):133-163. doi:10.1016/j.cll.2014.10.004 Patel MS, Carson JL. Anemia in the preoperative patient. Med Clin North Am. 2009;93(5):1095-1104. doi:10.1016/j.mcna.2009.05.007 requestBody: content: application/json: schema: $ref: "#/components/schemas/RPIBodyRequest" description: |- - `reticulocyte_percentage` (number, required): Reticulocyte percentage. Minimum: > 0, Maximum: <= 100. - `hematocrit` (number, required): Hematocrit value. Minimum: > 0. - `hematocrit_unit` (string, required): Unit of hematocrit measurement. Possible values: "percent", "L/L". - `normal_hematocrit` (number, optional): Normal hematocrit value. If not provided, defaults to 45%. Minimum: > 0. - `normal_hematocrit_unit` (string, optional): Unit of normal hematocrit measurement. Required if normal_hematocrit is provided. Possible values: "percent", "L/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/RPIBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Reticulocyte Production Index (RPI) tags: - Reticulocyte Production Index (RPI) /reynolds-cad-risk-men: post: description: | Calculate the Reynolds CAD Risk Score to estimate the 10-year risk of cardiovascular disease for non-diabetic men. References: Ridker PM, Paynter NP, Rifai N, Gaziano JM, Cook NR. C-reactive protein and parental history improve global cardiovascular risk prediction: the Reynolds Risk Score for men. Circulation. 2008;118(22):2243-2251. doi:10.1161/CIRCULATIONAHA.108.814251 requestBody: content: application/json: schema: $ref: "#/components/schemas/ReynoldsCADRiskMenBodyRequest" description: |- - `age` (integer, required): Age in years. Range: 30-80. - `systolic_blood_pressure` (number, required): Systolic blood pressure. Minimum: > 0. - `total_cholesterol` (number, required): Total cholesterol value. Minimum: > 0. - `total_cholesterol_unit` (string, required): Unit of total cholesterol measurement. Possible values: "mg/dL", "mmol/L". - `hdl_cholesterol` (number, required): HDL cholesterol value. Minimum: > 0. - `hdl_cholesterol_unit` (string, required): Unit of HDL cholesterol measurement. Possible values: "mg/dL", "mmol/L". - `high_sensitivity_crp` (number, required): High-sensitivity C-reactive protein value. Minimum: > 0. - `high_sensitivity_crp_unit` (string, required): Unit of high-sensitivity CRP measurement. Possible values: "mg/L", "mg/dL". - `smoker` (boolean, required): Whether the person is a smoker. - `family_history_mi` (boolean, required): Family history of myocardial infarction before age 60. required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/ReynoldsCADRiskMenBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Reynolds Cardiovascular Disease (CAD) Risk Score for non-diabetic Men tags: - Reynolds Cardiovascular Disease (CAD) Risk Score for non-diabetic Men /reynolds-cad-risk-women: post: description: | Calculate the Reynolds CAD Risk Score to estimate the 10-year risk of cardiovascular disease for women. References: Ridker PM, Buring JE, Rifai N, Cook NR. Development and validation of improved algorithms for the assessment of global cardiovascular risk in women: the Reynolds Risk S/* */core [published correction appears in JAMA. 2007 Apr 4;297(13):1433]. JAMA. 2007;297(6):611-619. doi:10.1001/jama.297.6.611 requestBody: content: application/json: schema: $ref: "#/components/schemas/ReynoldsCADRiskWomenBodyRequest" description: |- - `age` (integer, required): Age in years. Range: 30-80. - `systolic_blood_pressure` (number, required): Systolic blood pressure. Minimum: > 0. - `total_cholesterol` (number, required): Total cholesterol value. Minimum: > 0. - `total_cholesterol_unit` (string, required): Unit of total cholesterol measurement. Possible values: "mg/dL", "mmol/L". - `hdl_cholesterol` (number, required): HDL cholesterol value. Minimum: > 0. - `hdl_cholesterol_unit` (string, required): Unit of HDL cholesterol measurement. Possible values: "mg/dL", "mmol/L". - `high_sensitivity_crp` (number, required): High-sensitivity C-reactive protein value. Minimum: > 0. - `high_sensitivity_crp_unit` (string, required): Unit of high-sensitivity CRP measurement. Possible values: "mg/L", "mg/dL". - `smoker` (boolean, required): Whether the person is a smoker. - `family_history_mi` (boolean, required): Family history of myocardial infarction before age 60. - `hemoglobin_a1c` (number, optional): Hemoglobin A1c value. Required for diabetic patients. In %. Minimum: > 0. required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/ReynoldsCADRiskWomenBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Reynolds Cardiovascular Disease (CAD) Risk Score for Women tags: - Reynolds Cardiovascular Disease (CAD) Risk Score for Women /serum-ascites-albumin-gradient: post: description: | Calculate the Serum-Ascites Albumin Gradient (SAAG) based on serum albumin and ascites albumin levels. References: Runyon BA; AASLD Practice Guidelines Committee. Management of adult patients with ascites due to cirrhosis: an update. Hepatology. 2009;49(6):2087-2107. doi:10.1002/hep.22853 requestBody: content: application/json: schema: $ref: "#/components/schemas/SAAGBodyRequest" description: |- - `serum_albumin` (number, required): Serum albumin value. Minimum: > 0. - `serum_albumin_unit` (string, required): Unit of serum albumin measurement. Possible values: "g/dL", "g/L". - `ascites_albumin` (number, required): Ascites albumin value. Minimum: > 0. - `ascites_albumin_unit` (string, required): Unit of ascites albumin measurement. Possible values: "g/dL", "g/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/SAAGBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Serum-Ascites Albumin Gradient (SAAG) tags: - Serum-Ascites Albumin Gradient (SAAG) /shock-index: post: description: | Calculate Shock Index to identify early shock References: Allgöwer M, Burri C. The “shock-index”. Dtsch med Wochenschr 1967; 92(43): 1947-1950. DOI: 10.1055/s-0028-1106070 requestBody: content: application/json: schema: $ref: "#/components/schemas/ShockIndexBodyRequest" description: |- - `heart_rate` (number, required): Heart rate value (bpm). Minimum: > 0. - `systolic_blood_pressure` (number, required): Systolic blood pressure value (mmHg). Minimum: > 0. required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/ShockIndexBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Shock Index tags: - Shock Index /sodium-correction-hyperglycemia: post: description: | Calculate corrected sodium level in hyperglycemia using the Katz formula and Hillier method. References: Katz MA. Hyperglycemia-induced hyponatremia--calculation of expected serum sodium depression. N Engl J Med. 1973;289(16):843-844. doi:10.1056/NEJM197310182891607 Hillier TA, Abbott RD, Barrett EJ. Hyponatremia: evaluating the correction factor for hyperglycemia. Am J Med. 1999;106(4):399-403. doi:10.1016/s0002-9343(99)00055-8 requestBody: content: application/json: schema: $ref: "#/components/schemas/SodiumCorrectionBodyRequest" description: |- - `sodium` (number, required): Measured sodium level. Minimum: > 0. - `sodium_unit` (string, required): Unit of measured sodium. Possible values: "mmol/L", "mEq/L". - `glucose` (number, required): Measured glucose level. Minimum: > 0. - `glucose_unit` (string, required): Unit of glucose measurement. Possible values: "mg/dL", "mmol/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/SodiumCorrectionBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Sodium Correction for Hyperglycemia tags: - Sodium Correction for Hyperglycemia /systemic-immune-inflammation-index: post: description: | Calculate SII based on platelet count, neutrophil count, and lymphocyte count. References: Hu B, Yang XR, Xu Y, et al. Systemic immune-inflammation index predicts prognosis of patients after curative resection for hepatocellular carcinoma. Clin Cancer Res. 2014;20(23):6212-6222. doi:10.1158/1078-0432.CCR-14-0442 requestBody: content: application/json: schema: $ref: "#/components/schemas/SIIBodyRequest" description: |- - `platelet_count` (number, required): Platelet count. Minimum: > 0. - `platelet_count_unit` (string, required): Unit of platelet count. Possible values: "10^9/L", "10^3/µL". - `neutrophil_count` (number, required): Neutrophil count. Minimum: > 0. - `neutrophil_count_unit` (string, required): Unit of neutrophil count. Possible values: "10^9/L", "10^3/µL". - `lymphocyte_count` (number, required): Lymphocyte count. Minimum: > 0. - `lymphocyte_count_unit` (string, required): Unit of lymphocyte count. Possible values: "10^9/L", "10^3/µL". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/SIIBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Systemic Immune-Inflammation Index (SII) tags: - Systemic Immune-Inflammation Index (SII) /triglyceride-glucose-index: post: description: | Calculate the Triglyceride-Glucose Index (TyG), a marker of insulin resistance. References: Simental-Mendía LE, Rodríguez-Morán M, Guerrero-Romero F. The product of fasting glucose and triglycerides as surrogate for identifying insulin resistance in apparently healthy subjects. Metab Syndr Relat Disord. 2008;6(4):299-304. doi:10.1089/met.2008.0034 Araújo SP, Juvanhol LL, Bressan J, Hermsdorff HHM. Triglyceride glucose index: A new biomarker in predicting cardiovascular risk. Prev Med Rep. 2022;29:101941. Published 2022 Aug 24. doi:10.1016/j.pmedr.2022.101941 requestBody: content: application/json: schema: $ref: "#/components/schemas/TyGBodyRequest" description: |- - `triglycerides` (number, required): Triglycerides value. Minimum: > 0. - `triglycerides_unit` (string, required): Unit of triglycerides measurement. Possible values: "mg/dL", "mmol/L". - `glucose` (number, required): Glucose value. Minimum: > 0. - `glucose_unit` (string, required): Unit of glucose measurement. Possible values: "mg/dL", "mmol/L". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/TyGBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Triglyceride-Glucose Index (TyG) tags: - Triglyceride-Glucose Index (TyG) /unsaturated-iron-binding-capacity: post: description: Calculate UIBC based on TIBC and Serum Iron values requestBody: content: application/json: schema: $ref: "#/components/schemas/UIBCBodyRequest" description: |- - `tibc` (number, required): Total Iron Binding Capacity value. Minimum: >= 0. - `tibc_unit` (string, required): Unit of TIBC measurement. Possible values: "µmol/L", "mmol/L", "µg/dL". - `serum_iron` (number, required): Serum Iron value. Minimum: >= 0. - `serum_iron_unit` (string, required): Unit of Serum Iron measurement. Possible values: "µmol/L", "mmol/L", "µg/dL". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/UIBCBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Unsaturated Iron Binding Capacity (UIBC) tags: - Unsaturated Iron Binding Capacity (UIBC) /visceral-adiposity-index: post: description: | Calculate Visceral Adiposity Index (VAI) as an indicator of visceral adipose function References: Amato MC, Giordano C, Galia M, et al. Visceral Adiposity Index: a reliable indicator of visceral fat function associated with cardiometabolic risk. Diabetes Care. 2010;33(4):920-922. doi:10.2337/dc09-1825 requestBody: content: application/json: schema: $ref: "#/components/schemas/VAIBodyRequest" description: |- - `gender` (string, required): Gender of the person. Possible values: "male", "female". - `waist_circumference` (number, required): Waist circumference. Minimum: > 0. - `waist_circumference_unit` (string, required): Unit of waist circumference measurement. Possible values: "cm", "in". - `bmi` (number, required): Body Mass Index (BMI). Minimum: > 0. - `triglycerides` (number, required): Triglycerides value. Minimum: > 0. - `triglycerides_unit` (string, required): Unit of triglycerides measurement. Possible values: "mmol/L", "mg/dL". - `hdl_cholesterol` (number, required): HDL cholesterol value. Minimum: > 0. - `hdl_cholesterol_unit` (string, required): Unit of HDL cholesterol measurement. Possible values: "mmol/L", "mg/dL". required: true responses: "200": content: application/json: schema: $ref: "#/components/schemas/VAIBodyResponse" description: OK default: content: application/problem+json: schema: $ref: "#/components/schemas/ErrorModel" description: Error summary: Visceral Adiposity Index (VAI) tags: - Visceral Adiposity Index (VAI) servers: - url: https://calculate-blood-api-calculatedbody-62dd8c13.koyeb.app